Acute gastroenteritis and the usage pattern of antibiotics and traditional herbal medications for its management in a Nigerian community.

Acute gastroenteritis (AGE) is the highest cause of mortality worldwide in children under the age of 5 years, with the highest mortalities occurring in low-to-middle income countries. Treatment can involve use of unregulated herbal medication and antibiotics. A cross sectional study was carried out...

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Autores principales:	Oluwapelumi Olufemi Adeyemi, Ade Stephen Alabi, Oluwasanmi Anuoluwapo Adeyemi, Olaoluwa Temitope Talabi, Oreoluwa M Abidakun, Ireoluwa Yinka Joel, Nicola J Stonehouse
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/0cff2f82d1374c39967b10af3152f821
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spelling	oai:doaj.org-article:0cff2f82d1374c39967b10af3152f8212021-12-02T20:17:22ZAcute gastroenteritis and the usage pattern of antibiotics and traditional herbal medications for its management in a Nigerian community.1932-620310.1371/journal.pone.0257837https://doaj.org/article/0cff2f82d1374c39967b10af3152f8212021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0257837https://doaj.org/toc/1932-6203Acute gastroenteritis (AGE) is the highest cause of mortality worldwide in children under the age of 5 years, with the highest mortalities occurring in low-to-middle income countries. Treatment can involve use of unregulated herbal medication and antibiotics. A cross sectional study was carried out to investigate the use of antibiotics and traditional herbal medications in the management of AGE among Yòrùbá-speaking communities in Kwara State, Nigeria. Our findings suggest habitual use of antibiotics (54.6%) and herbal medication (42.5%) in the management of AGE with high levels of self-prescription of antibiotics (21.7%) and herbal medications (36.2%) within the community. Ethanolic extracts of selected herbal plants reported (i.e. Aristolochia ringens, Azadirachta indica, Chromolaena odorata, Etanda Africana, Ficus capensis, Ficus vogelii, Mangifera indica, Momordica charantia, Ocimum gratisimum, Senna alata, Sorghum bicolor and Vernonia amygdalina) were investigated for antibacterial properties, using bacteria known to be causative agents of AGE. Our findings showed that, with exception of Ficus vogelii, which enhanced bacterial growth, the plant extracts reported all showed some antibacterial activity. We further discuss our findings within a regulatory context, with the aim to guide the use of traditional and herbal medication in low-to medium income countries (LMICs) and reduce the potential risks associated with the development of antimicrobial resistance.Oluwapelumi Olufemi AdeyemiAde Stephen AlabiOluwasanmi Anuoluwapo AdeyemiOlaoluwa Temitope TalabiOreoluwa M AbidakunIreoluwa Yinka JoelNicola J StonehousePublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 10, p e0257837 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Oluwapelumi Olufemi Adeyemi Ade Stephen Alabi Oluwasanmi Anuoluwapo Adeyemi Olaoluwa Temitope Talabi Oreoluwa M Abidakun Ireoluwa Yinka Joel Nicola J Stonehouse Acute gastroenteritis and the usage pattern of antibiotics and traditional herbal medications for its management in a Nigerian community.
description	Acute gastroenteritis (AGE) is the highest cause of mortality worldwide in children under the age of 5 years, with the highest mortalities occurring in low-to-middle income countries. Treatment can involve use of unregulated herbal medication and antibiotics. A cross sectional study was carried out to investigate the use of antibiotics and traditional herbal medications in the management of AGE among Yòrùbá-speaking communities in Kwara State, Nigeria. Our findings suggest habitual use of antibiotics (54.6%) and herbal medication (42.5%) in the management of AGE with high levels of self-prescription of antibiotics (21.7%) and herbal medications (36.2%) within the community. Ethanolic extracts of selected herbal plants reported (i.e. Aristolochia ringens, Azadirachta indica, Chromolaena odorata, Etanda Africana, Ficus capensis, Ficus vogelii, Mangifera indica, Momordica charantia, Ocimum gratisimum, Senna alata, Sorghum bicolor and Vernonia amygdalina) were investigated for antibacterial properties, using bacteria known to be causative agents of AGE. Our findings showed that, with exception of Ficus vogelii, which enhanced bacterial growth, the plant extracts reported all showed some antibacterial activity. We further discuss our findings within a regulatory context, with the aim to guide the use of traditional and herbal medication in low-to medium income countries (LMICs) and reduce the potential risks associated with the development of antimicrobial resistance.
format	article
author	Oluwapelumi Olufemi Adeyemi Ade Stephen Alabi Oluwasanmi Anuoluwapo Adeyemi Olaoluwa Temitope Talabi Oreoluwa M Abidakun Ireoluwa Yinka Joel Nicola J Stonehouse
author_facet	Oluwapelumi Olufemi Adeyemi Ade Stephen Alabi Oluwasanmi Anuoluwapo Adeyemi Olaoluwa Temitope Talabi Oreoluwa M Abidakun Ireoluwa Yinka Joel Nicola J Stonehouse
author_sort	Oluwapelumi Olufemi Adeyemi
title	Acute gastroenteritis and the usage pattern of antibiotics and traditional herbal medications for its management in a Nigerian community.
title_short	Acute gastroenteritis and the usage pattern of antibiotics and traditional herbal medications for its management in a Nigerian community.
title_full	Acute gastroenteritis and the usage pattern of antibiotics and traditional herbal medications for its management in a Nigerian community.
title_fullStr	Acute gastroenteritis and the usage pattern of antibiotics and traditional herbal medications for its management in a Nigerian community.
title_full_unstemmed	Acute gastroenteritis and the usage pattern of antibiotics and traditional herbal medications for its management in a Nigerian community.
title_sort	acute gastroenteritis and the usage pattern of antibiotics and traditional herbal medications for its management in a nigerian community.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/0cff2f82d1374c39967b10af3152f821
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Acute gastroenteritis and the usage pattern of antibiotics and traditional herbal medications for its management in a Nigerian community.

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