Tenascin C promiscuously binds growth factors via its fifth fibronectin type III-like domain.

Tenascin C promiscuously binds growth factors via its fifth fibronectin type III-like domain.

Tenascin C (TNC) is an extracellular matrix protein that is upregulated during development as well as tissue remodeling. TNC is comprised of multiple independent folding domains, including 15 fibronectin type III-like (TNCIII) domains. The fifth TNCIII domain (TNCIII5) has previously been shown to b...

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Autores principales: Laura De Laporte, Jeffrey J Rice, Federico Tortelli, Jeffrey A Hubbell
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/0d11729b46f74c659bd939bb767b6f8f
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