Radiotherapy for Recurrent Keloid: A Case Report

Background: Keloid is a benign growth of connective tissue. There are several risk factors that play a role in keloid growth. Excision surgery is one of the modalities in the treatment of keloids. However, excision surgery alone has a recurrence rate of 45-100%. Case: Male, 37 years old, with compl...

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Autores principales:	Christina Hari Nawangsih Prihharsanti, Muhamad Rizqi Setyarto, Dion Firli Bramantyo
Formato:	article
Lenguaje:	EN
Publicado:	Diponegoro University 2020
Materias:	keloids recurrence radiotherapy. Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/0d123cc3cdf8488183942301d5574b4e
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spelling	oai:doaj.org-article:0d123cc3cdf8488183942301d5574b4e2021-11-05T16:47:43ZRadiotherapy for Recurrent Keloid: A Case Report2503-217810.14710/jbtr.v6i3.8473https://doaj.org/article/0d123cc3cdf8488183942301d5574b4e2020-12-01T00:00:00Zhttps://ejournal2.undip.ac.id/index.php/jbtr/article/view/8473https://doaj.org/toc/2503-2178Background: Keloid is a benign growth of connective tissue. There are several risk factors that play a role in keloid growth. Excision surgery is one of the modalities in the treatment of keloids. However, excision surgery alone has a recurrence rate of 45-100%. Case: Male, 37 years old, with complaints arising from a keloid lesions in the left earlobe since three years ago with a history of previous injuries. The lesions is then operated on but always grows back postoperatively. The number of surgeries that have been carried out three times with further treatment in the form of corticosteroid injection. However, keloid still recurrence. Finally it was decided to undergo treatment with surgery followed by radiotherapy within a period of no more than 24 hours postoperatively. Follow-up after six months gave good results without recurrence. Discussion: Keloid has a high recurrence rate after excision surgery. Surgery followed by radiotherapy has a low recurrence rate compared to surgery or surgery followed by administration of corticosteroid injections. Radiotherapy as adjuvant therapy for postoperative keloid excision has the role of sterilizing the connective tissue stem cell active fibroblasts and acute inflammatory cells that grow in the early postoperative period. A study states that administration of postoperative radiation with electrons in keloids in the earlobe at a dose of 15 Gy in three fractions gives a low recurrence rate and a low risk of side effects in the surrounding soft tissue.Christina Hari Nawangsih PrihharsantiMuhamad Rizqi SetyartoDion Firli BramantyoDiponegoro Universityarticlekeloidsrecurrenceradiotherapy.Medicine (General)R5-920ENJournal of Biomedicine and Translational Research, Vol 6, Iss 3, Pp 89-91 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	keloids recurrence radiotherapy. Medicine (General) R5-920
spellingShingle	keloids recurrence radiotherapy. Medicine (General) R5-920 Christina Hari Nawangsih Prihharsanti Muhamad Rizqi Setyarto Dion Firli Bramantyo Radiotherapy for Recurrent Keloid: A Case Report
description	Background: Keloid is a benign growth of connective tissue. There are several risk factors that play a role in keloid growth. Excision surgery is one of the modalities in the treatment of keloids. However, excision surgery alone has a recurrence rate of 45-100%. Case: Male, 37 years old, with complaints arising from a keloid lesions in the left earlobe since three years ago with a history of previous injuries. The lesions is then operated on but always grows back postoperatively. The number of surgeries that have been carried out three times with further treatment in the form of corticosteroid injection. However, keloid still recurrence. Finally it was decided to undergo treatment with surgery followed by radiotherapy within a period of no more than 24 hours postoperatively. Follow-up after six months gave good results without recurrence. Discussion: Keloid has a high recurrence rate after excision surgery. Surgery followed by radiotherapy has a low recurrence rate compared to surgery or surgery followed by administration of corticosteroid injections. Radiotherapy as adjuvant therapy for postoperative keloid excision has the role of sterilizing the connective tissue stem cell active fibroblasts and acute inflammatory cells that grow in the early postoperative period. A study states that administration of postoperative radiation with electrons in keloids in the earlobe at a dose of 15 Gy in three fractions gives a low recurrence rate and a low risk of side effects in the surrounding soft tissue.
format	article
author	Christina Hari Nawangsih Prihharsanti Muhamad Rizqi Setyarto Dion Firli Bramantyo
author_facet	Christina Hari Nawangsih Prihharsanti Muhamad Rizqi Setyarto Dion Firli Bramantyo
author_sort	Christina Hari Nawangsih Prihharsanti
title	Radiotherapy for Recurrent Keloid: A Case Report
title_short	Radiotherapy for Recurrent Keloid: A Case Report
title_full	Radiotherapy for Recurrent Keloid: A Case Report
title_fullStr	Radiotherapy for Recurrent Keloid: A Case Report
title_full_unstemmed	Radiotherapy for Recurrent Keloid: A Case Report
title_sort	radiotherapy for recurrent keloid: a case report
publisher	Diponegoro University
publishDate	2020
url	https://doaj.org/article/0d123cc3cdf8488183942301d5574b4e
work_keys_str_mv	AT christinaharinawangsihprihharsanti radiotherapyforrecurrentkeloidacasereport AT muhamadrizqisetyarto radiotherapyforrecurrentkeloidacasereport AT dionfirlibramantyo radiotherapyforrecurrentkeloidacasereport
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Radiotherapy for Recurrent Keloid: A Case Report

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