Fluorescence Image-Guided Navigation Surgery Using Indocyanine Green for Hepatoblastoma

In the past decade, navigation surgery using fluorescent indocyanine green (ICG) dye for hepatoblastoma (HB) has been developed for the resection of primary or metastatic tumors. Since HB cells can take up ICG but cannot excrete it to the bile duct, ICG remains in the HB cells, which can be used for...

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Autor principal:	Eiso Hiyama
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	indocyanine green navigation hepatoblastoma hepatectomy metastasectomy tumor burden Pediatrics RJ1-570
Acceso en línea:	https://doaj.org/article/0d13faefbb344889a92d279a459c9a46
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spelling	oai:doaj.org-article:0d13faefbb344889a92d279a459c9a462021-11-25T17:14:33ZFluorescence Image-Guided Navigation Surgery Using Indocyanine Green for Hepatoblastoma10.3390/children81110152227-9067https://doaj.org/article/0d13faefbb344889a92d279a459c9a462021-11-01T00:00:00Zhttps://www.mdpi.com/2227-9067/8/11/1015https://doaj.org/toc/2227-9067In the past decade, navigation surgery using fluorescent indocyanine green (ICG) dye for hepatoblastoma (HB) has been developed for the resection of primary or metastatic tumors. Since HB cells can take up ICG but cannot excrete it to the bile duct, ICG remains in the HB cells, which can be used for navigation by fluorescent activation. The complete resection of the primary tumor as well as metastatic tumors, along with appropriate neoadjuvant and adjuvant chemotherapy, is essential for cure. ICG fluorescence can detect microscopic residual lesions in the primary lesion and identify micro-metastases in the lung or other lesions; consequently, ICG navigation surgery may improve outcomes for patients with HB. The basic technique and recent advances in ICG navigation for HB surgery are reviewed.Eiso HiyamaMDPI AGarticleindocyanine greennavigationhepatoblastomahepatectomymetastasectomytumor burdenPediatricsRJ1-570ENChildren, Vol 8, Iss 1015, p 1015 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	indocyanine green navigation hepatoblastoma hepatectomy metastasectomy tumor burden Pediatrics RJ1-570
spellingShingle	indocyanine green navigation hepatoblastoma hepatectomy metastasectomy tumor burden Pediatrics RJ1-570 Eiso Hiyama Fluorescence Image-Guided Navigation Surgery Using Indocyanine Green for Hepatoblastoma
description	In the past decade, navigation surgery using fluorescent indocyanine green (ICG) dye for hepatoblastoma (HB) has been developed for the resection of primary or metastatic tumors. Since HB cells can take up ICG but cannot excrete it to the bile duct, ICG remains in the HB cells, which can be used for navigation by fluorescent activation. The complete resection of the primary tumor as well as metastatic tumors, along with appropriate neoadjuvant and adjuvant chemotherapy, is essential for cure. ICG fluorescence can detect microscopic residual lesions in the primary lesion and identify micro-metastases in the lung or other lesions; consequently, ICG navigation surgery may improve outcomes for patients with HB. The basic technique and recent advances in ICG navigation for HB surgery are reviewed.
format	article
author	Eiso Hiyama
author_facet	Eiso Hiyama
author_sort	Eiso Hiyama
title	Fluorescence Image-Guided Navigation Surgery Using Indocyanine Green for Hepatoblastoma
title_short	Fluorescence Image-Guided Navigation Surgery Using Indocyanine Green for Hepatoblastoma
title_full	Fluorescence Image-Guided Navigation Surgery Using Indocyanine Green for Hepatoblastoma
title_fullStr	Fluorescence Image-Guided Navigation Surgery Using Indocyanine Green for Hepatoblastoma
title_full_unstemmed	Fluorescence Image-Guided Navigation Surgery Using Indocyanine Green for Hepatoblastoma
title_sort	fluorescence image-guided navigation surgery using indocyanine green for hepatoblastoma
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/0d13faefbb344889a92d279a459c9a46
work_keys_str_mv	AT eisohiyama fluorescenceimageguidednavigationsurgeryusingindocyaninegreenforhepatoblastoma
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Fluorescence Image-Guided Navigation Surgery Using Indocyanine Green for Hepatoblastoma

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