Stability of SARS-CoV-2 on critical personal protective equipment

Abstract The spread of COVID-19 in healthcare settings is concerning, with healthcare workers representing a disproportionately high percentage of confirmed cases. Although SARS-CoV-2 virus has been found to persist on surfaces for a number of days, the extent and duration of fomites as a mode of tr...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Samantha B. Kasloff, Anders Leung, James E. Strong, Duane Funk, Todd Cutts
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/0d14e3d4949746728e9eb5557ec26c54
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:0d14e3d4949746728e9eb5557ec26c54
record_format	dspace
spelling	oai:doaj.org-article:0d14e3d4949746728e9eb5557ec26c542021-12-02T14:12:09ZStability of SARS-CoV-2 on critical personal protective equipment10.1038/s41598-020-80098-32045-2322https://doaj.org/article/0d14e3d4949746728e9eb5557ec26c542021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-80098-3https://doaj.org/toc/2045-2322Abstract The spread of COVID-19 in healthcare settings is concerning, with healthcare workers representing a disproportionately high percentage of confirmed cases. Although SARS-CoV-2 virus has been found to persist on surfaces for a number of days, the extent and duration of fomites as a mode of transmission, particularly in healthcare settings, has not been fully characterized. To shed light on this critical matter, the present study provides the first comprehensive assessment of SARS-CoV-2 stability on experimentally contaminated personal protective equipment (PPE) widely used by healthcare workers and the general public. Persistence of viable virus was monitored over 21 days on eight different materials, including nitrile medical examination gloves, reinforced chemical resistant gloves, N-95 and N-100 particulate respirator masks, Tyvek, plastic, cotton, and stainless steel. Unlike previous reports, viable SARS-CoV-2 in the presence of a soil load persisted for up to 21 days on experimentally inoculated PPE, including materials from filtering facepiece respirators (N-95 and N-100 masks) and a plastic visor. Conversely, when applied to 100% cotton fabric, the virus underwent rapid degradation and became undetectable by TCID50 assay within 24 h. These findings underline the importance of appropriate handling of contaminated PPE during and following use in high-risk settings and provide interesting insight into the potential utility of cotton in limiting COVID-19 transmission.Samantha B. KasloffAnders LeungJames E. StrongDuane FunkTodd CuttsNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Samantha B. Kasloff Anders Leung James E. Strong Duane Funk Todd Cutts Stability of SARS-CoV-2 on critical personal protective equipment
description	Abstract The spread of COVID-19 in healthcare settings is concerning, with healthcare workers representing a disproportionately high percentage of confirmed cases. Although SARS-CoV-2 virus has been found to persist on surfaces for a number of days, the extent and duration of fomites as a mode of transmission, particularly in healthcare settings, has not been fully characterized. To shed light on this critical matter, the present study provides the first comprehensive assessment of SARS-CoV-2 stability on experimentally contaminated personal protective equipment (PPE) widely used by healthcare workers and the general public. Persistence of viable virus was monitored over 21 days on eight different materials, including nitrile medical examination gloves, reinforced chemical resistant gloves, N-95 and N-100 particulate respirator masks, Tyvek, plastic, cotton, and stainless steel. Unlike previous reports, viable SARS-CoV-2 in the presence of a soil load persisted for up to 21 days on experimentally inoculated PPE, including materials from filtering facepiece respirators (N-95 and N-100 masks) and a plastic visor. Conversely, when applied to 100% cotton fabric, the virus underwent rapid degradation and became undetectable by TCID50 assay within 24 h. These findings underline the importance of appropriate handling of contaminated PPE during and following use in high-risk settings and provide interesting insight into the potential utility of cotton in limiting COVID-19 transmission.
format	article
author	Samantha B. Kasloff Anders Leung James E. Strong Duane Funk Todd Cutts
author_facet	Samantha B. Kasloff Anders Leung James E. Strong Duane Funk Todd Cutts
author_sort	Samantha B. Kasloff
title	Stability of SARS-CoV-2 on critical personal protective equipment
title_short	Stability of SARS-CoV-2 on critical personal protective equipment
title_full	Stability of SARS-CoV-2 on critical personal protective equipment
title_fullStr	Stability of SARS-CoV-2 on critical personal protective equipment
title_full_unstemmed	Stability of SARS-CoV-2 on critical personal protective equipment
title_sort	stability of sars-cov-2 on critical personal protective equipment
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0d14e3d4949746728e9eb5557ec26c54
work_keys_str_mv	AT samanthabkasloff stabilityofsarscov2oncriticalpersonalprotectiveequipment AT andersleung stabilityofsarscov2oncriticalpersonalprotectiveequipment AT jamesestrong stabilityofsarscov2oncriticalpersonalprotectiveequipment AT duanefunk stabilityofsarscov2oncriticalpersonalprotectiveequipment AT toddcutts stabilityofsarscov2oncriticalpersonalprotectiveequipment
_version_	1718391766638395392

Stability of SARS-CoV-2 on critical personal protective equipment

Ejemplares similares