HYPOVITAMINOSIS D, CORTICAL AND SUB-CORTICAL COGNITIVE FUNCTIONING DEFICTS IN PATIENTS WITH PARKINSON'S DISEASE DEMENTIA

Objective: To examine vitamin D status and its association with cortical/sub-cortical cognitive functioning in patients with Parkinson’s Disease Dementia. Study Design: Cross sectional study. Place and Duration of Study: Bahawal Victoria Hospital, Civil Hospital and Nishter Hospital Pakista...

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Autores principales:	Amara Gul, Javed Yousaf
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2018
Materias:	vitamin d dementia cognition Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/0d1bfdb7870a4600847ca8d3e1e3b340
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spelling	oai:doaj.org-article:0d1bfdb7870a4600847ca8d3e1e3b3402021-11-26T03:04:44ZHYPOVITAMINOSIS D, CORTICAL AND SUB-CORTICAL COGNITIVE FUNCTIONING DEFICTS IN PATIENTS WITH PARKINSON'S DISEASE DEMENTIA0030-96482411-8842https://doaj.org/article/0d1bfdb7870a4600847ca8d3e1e3b3402018-12-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/2556/2094https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To examine vitamin D status and its association with cortical/sub-cortical cognitive functioning in patients with Parkinson’s Disease Dementia. Study Design: Cross sectional study. Place and Duration of Study: Bahawal Victoria Hospital, Civil Hospital and Nishter Hospital Pakistan during May 2016 to June 2017. Material and Methods: Fifty patients diagnosed with PDD at Bahawal Victoria Hospital, Civil Hospital and Nishter Hospital Pakistan during May 2016 until June 2017 and fifty healthy individuals participated in the study. Blood samples were examined for serum 25 hydroxy vitamin D. Following, Parkinson’s disease cognitive rating scale was administered to assess cortical and sub-cortical cognitive functioning. Results: Results showed that patients with PDD were deficient in serum 25 hydroxy vitamin D and cortical/subcortical cognitive functioning in contrast with healthy individuals. Serum 25 hydroxy Vitamin D and education level of patients with PDD were significant predictors of cortical and subcortical cognitive impairment. Conclusion: Hypovitaminosis D is a biomarker of cortical and subcortical cognitive deficits in patients with PDD.Amara GulJaved YousafArmy Medical College Rawalpindiarticlevitamin ddementiacognitionMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 68, Iss 6, Pp 1605-1608 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	vitamin d dementia cognition Medicine R Medicine (General) R5-920
spellingShingle	vitamin d dementia cognition Medicine R Medicine (General) R5-920 Amara Gul Javed Yousaf HYPOVITAMINOSIS D, CORTICAL AND SUB-CORTICAL COGNITIVE FUNCTIONING DEFICTS IN PATIENTS WITH PARKINSON'S DISEASE DEMENTIA
description	Objective: To examine vitamin D status and its association with cortical/sub-cortical cognitive functioning in patients with Parkinson’s Disease Dementia. Study Design: Cross sectional study. Place and Duration of Study: Bahawal Victoria Hospital, Civil Hospital and Nishter Hospital Pakistan during May 2016 to June 2017. Material and Methods: Fifty patients diagnosed with PDD at Bahawal Victoria Hospital, Civil Hospital and Nishter Hospital Pakistan during May 2016 until June 2017 and fifty healthy individuals participated in the study. Blood samples were examined for serum 25 hydroxy vitamin D. Following, Parkinson’s disease cognitive rating scale was administered to assess cortical and sub-cortical cognitive functioning. Results: Results showed that patients with PDD were deficient in serum 25 hydroxy vitamin D and cortical/subcortical cognitive functioning in contrast with healthy individuals. Serum 25 hydroxy Vitamin D and education level of patients with PDD were significant predictors of cortical and subcortical cognitive impairment. Conclusion: Hypovitaminosis D is a biomarker of cortical and subcortical cognitive deficits in patients with PDD.
format	article
author	Amara Gul Javed Yousaf
author_facet	Amara Gul Javed Yousaf
author_sort	Amara Gul
title	HYPOVITAMINOSIS D, CORTICAL AND SUB-CORTICAL COGNITIVE FUNCTIONING DEFICTS IN PATIENTS WITH PARKINSON'S DISEASE DEMENTIA
title_short	HYPOVITAMINOSIS D, CORTICAL AND SUB-CORTICAL COGNITIVE FUNCTIONING DEFICTS IN PATIENTS WITH PARKINSON'S DISEASE DEMENTIA
title_full	HYPOVITAMINOSIS D, CORTICAL AND SUB-CORTICAL COGNITIVE FUNCTIONING DEFICTS IN PATIENTS WITH PARKINSON'S DISEASE DEMENTIA
title_fullStr	HYPOVITAMINOSIS D, CORTICAL AND SUB-CORTICAL COGNITIVE FUNCTIONING DEFICTS IN PATIENTS WITH PARKINSON'S DISEASE DEMENTIA
title_full_unstemmed	HYPOVITAMINOSIS D, CORTICAL AND SUB-CORTICAL COGNITIVE FUNCTIONING DEFICTS IN PATIENTS WITH PARKINSON'S DISEASE DEMENTIA
title_sort	hypovitaminosis d, cortical and sub-cortical cognitive functioning deficts in patients with parkinson's disease dementia
publisher	Army Medical College Rawalpindi
publishDate	2018
url	https://doaj.org/article/0d1bfdb7870a4600847ca8d3e1e3b340
work_keys_str_mv	AT amaragul hypovitaminosisdcorticalandsubcorticalcognitivefunctioningdefictsinpatientswithparkinsonsdiseasedementia AT javedyousaf hypovitaminosisdcorticalandsubcorticalcognitivefunctioningdefictsinpatientswithparkinsonsdiseasedementia
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HYPOVITAMINOSIS D, CORTICAL AND SUB-CORTICAL COGNITIVE FUNCTIONING DEFICTS IN PATIENTS WITH PARKINSON'S DISEASE DEMENTIA

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