Clinically compliant spatial and temporal imaging of chimeric antigen receptor T-cells

Adoptive transfer of chimeric antigen receptor (CAR) T cells has shown promising anticancer results in clinical trials. Here the authors use the human sodium iodide symporter (hNIS) as a reporter gene to image human CAR T cells in cancer-bearing mice using broadly available tracers and imaging platf...

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Autores principales:	Nia Emami-Shahri, Julie Foster, Roxana Kashani, Patrycja Gazinska, Celia Cook, Jane Sosabowski, John Maher, Sophie Papa
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0d1c57bc0c364c149307c2471f782318
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spelling	oai:doaj.org-article:0d1c57bc0c364c149307c2471f7823182021-12-02T17:32:46ZClinically compliant spatial and temporal imaging of chimeric antigen receptor T-cells10.1038/s41467-018-03524-12041-1723https://doaj.org/article/0d1c57bc0c364c149307c2471f7823182018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03524-1https://doaj.org/toc/2041-1723Adoptive transfer of chimeric antigen receptor (CAR) T cells has shown promising anticancer results in clinical trials. Here the authors use the human sodium iodide symporter (hNIS) as a reporter gene to image human CAR T cells in cancer-bearing mice using broadly available tracers and imaging platforms.Nia Emami-ShahriJulie FosterRoxana KashaniPatrycja GazinskaCelia CookJane SosabowskiJohn MaherSophie PapaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nia Emami-Shahri Julie Foster Roxana Kashani Patrycja Gazinska Celia Cook Jane Sosabowski John Maher Sophie Papa Clinically compliant spatial and temporal imaging of chimeric antigen receptor T-cells
description	Adoptive transfer of chimeric antigen receptor (CAR) T cells has shown promising anticancer results in clinical trials. Here the authors use the human sodium iodide symporter (hNIS) as a reporter gene to image human CAR T cells in cancer-bearing mice using broadly available tracers and imaging platforms.
format	article
author	Nia Emami-Shahri Julie Foster Roxana Kashani Patrycja Gazinska Celia Cook Jane Sosabowski John Maher Sophie Papa
author_facet	Nia Emami-Shahri Julie Foster Roxana Kashani Patrycja Gazinska Celia Cook Jane Sosabowski John Maher Sophie Papa
author_sort	Nia Emami-Shahri
title	Clinically compliant spatial and temporal imaging of chimeric antigen receptor T-cells
title_short	Clinically compliant spatial and temporal imaging of chimeric antigen receptor T-cells
title_full	Clinically compliant spatial and temporal imaging of chimeric antigen receptor T-cells
title_fullStr	Clinically compliant spatial and temporal imaging of chimeric antigen receptor T-cells
title_full_unstemmed	Clinically compliant spatial and temporal imaging of chimeric antigen receptor T-cells
title_sort	clinically compliant spatial and temporal imaging of chimeric antigen receptor t-cells
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/0d1c57bc0c364c149307c2471f782318
work_keys_str_mv	AT niaemamishahri clinicallycompliantspatialandtemporalimagingofchimericantigenreceptortcells AT juliefoster clinicallycompliantspatialandtemporalimagingofchimericantigenreceptortcells AT roxanakashani clinicallycompliantspatialandtemporalimagingofchimericantigenreceptortcells AT patrycjagazinska clinicallycompliantspatialandtemporalimagingofchimericantigenreceptortcells AT celiacook clinicallycompliantspatialandtemporalimagingofchimericantigenreceptortcells AT janesosabowski clinicallycompliantspatialandtemporalimagingofchimericantigenreceptortcells AT johnmaher clinicallycompliantspatialandtemporalimagingofchimericantigenreceptortcells AT sophiepapa clinicallycompliantspatialandtemporalimagingofchimericantigenreceptortcells
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Clinically compliant spatial and temporal imaging of chimeric antigen receptor T-cells

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