Spinal cord injury causes chronic bone marrow failure

Spinal cord injury causes chronic bone marrow failure

Spinal cord injury (SCI) often leads to immune dysfunction, but mechanistic insights are still lacking. Here the authors show that SCI alters chemokine signaling and induces long, persisting defects in hematopoietic stem and progenitor cell migration, thereby entrapping them in the bone marrow and d...

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Autores principales: Randall S. Carpenter, Jessica M. Marbourg, Faith H. Brennan, Katherine A. Mifflin, Jodie C. E. Hall, Roselyn R. Jiang, Xiaokui M. Mo, Malith Karunasiri, Matthew H. Burke, Adrienne M. Dorrance, Phillip G. Popovich
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/0d1de6f876b2431485cb553f43443b20
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