Minimal barriers to invasion during human colorectal tumor growth

Invasion is a critical step in tumor development. Here, in colorectal cancer, the authors show that multiclonal invasion of the muscularis mucosae is pervasive, suggesting that invasive capacity is not a significant bottleneck in the evolution of the disease.

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Autores principales:	Marc D. Ryser, Diego Mallo, Allison Hall, Timothy Hardman, Lorraine M. King, Sergei Tatishchev, Inmaculada C. Sorribes, Carlo C. Maley, Jeffrey R. Marks, E. Shelley Hwang, Darryl Shibata
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0d25956044414a47b376fdedd27dfad9
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spelling	oai:doaj.org-article:0d25956044414a47b376fdedd27dfad92021-12-02T15:39:10ZMinimal barriers to invasion during human colorectal tumor growth10.1038/s41467-020-14908-72041-1723https://doaj.org/article/0d25956044414a47b376fdedd27dfad92020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14908-7https://doaj.org/toc/2041-1723Invasion is a critical step in tumor development. Here, in colorectal cancer, the authors show that multiclonal invasion of the muscularis mucosae is pervasive, suggesting that invasive capacity is not a significant bottleneck in the evolution of the disease.Marc D. RyserDiego MalloAllison HallTimothy HardmanLorraine M. KingSergei TatishchevInmaculada C. SorribesCarlo C. MaleyJeffrey R. MarksE. Shelley HwangDarryl ShibataNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Marc D. Ryser Diego Mallo Allison Hall Timothy Hardman Lorraine M. King Sergei Tatishchev Inmaculada C. Sorribes Carlo C. Maley Jeffrey R. Marks E. Shelley Hwang Darryl Shibata Minimal barriers to invasion during human colorectal tumor growth
description	Invasion is a critical step in tumor development. Here, in colorectal cancer, the authors show that multiclonal invasion of the muscularis mucosae is pervasive, suggesting that invasive capacity is not a significant bottleneck in the evolution of the disease.
format	article
author	Marc D. Ryser Diego Mallo Allison Hall Timothy Hardman Lorraine M. King Sergei Tatishchev Inmaculada C. Sorribes Carlo C. Maley Jeffrey R. Marks E. Shelley Hwang Darryl Shibata
author_facet	Marc D. Ryser Diego Mallo Allison Hall Timothy Hardman Lorraine M. King Sergei Tatishchev Inmaculada C. Sorribes Carlo C. Maley Jeffrey R. Marks E. Shelley Hwang Darryl Shibata
author_sort	Marc D. Ryser
title	Minimal barriers to invasion during human colorectal tumor growth
title_short	Minimal barriers to invasion during human colorectal tumor growth
title_full	Minimal barriers to invasion during human colorectal tumor growth
title_fullStr	Minimal barriers to invasion during human colorectal tumor growth
title_full_unstemmed	Minimal barriers to invasion during human colorectal tumor growth
title_sort	minimal barriers to invasion during human colorectal tumor growth
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/0d25956044414a47b376fdedd27dfad9
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Minimal barriers to invasion during human colorectal tumor growth

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