Multiple novel gene-by-environment interactions modify the effect of FTO variants on body mass index

Common variants in the fat mass and obesity associated (FTO) gene are linked to body mass index (BMI). Using the latest UK Biobank data, this study shows novel gene x environment interactions between FTOand lifestyle factors, including frequency of alcohol consumption, sleep, and added dietary salt.

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Detalles Bibliográficos
Autores principales:	Alexander I. Young, Fabian Wauthier, Peter Donnelly
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0d2d3074601b463b82844c074a61ce01
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spelling	oai:doaj.org-article:0d2d3074601b463b82844c074a61ce012021-12-02T14:38:57ZMultiple novel gene-by-environment interactions modify the effect of FTO variants on body mass index10.1038/ncomms127242041-1723https://doaj.org/article/0d2d3074601b463b82844c074a61ce012016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12724https://doaj.org/toc/2041-1723Common variants in the fat mass and obesity associated (FTO) gene are linked to body mass index (BMI). Using the latest UK Biobank data, this study shows novel gene x environment interactions between FTOand lifestyle factors, including frequency of alcohol consumption, sleep, and added dietary salt.Alexander I. YoungFabian WauthierPeter DonnellyNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Alexander I. Young Fabian Wauthier Peter Donnelly Multiple novel gene-by-environment interactions modify the effect of FTO variants on body mass index
description	Common variants in the fat mass and obesity associated (FTO) gene are linked to body mass index (BMI). Using the latest UK Biobank data, this study shows novel gene x environment interactions between FTOand lifestyle factors, including frequency of alcohol consumption, sleep, and added dietary salt.
format	article
author	Alexander I. Young Fabian Wauthier Peter Donnelly
author_facet	Alexander I. Young Fabian Wauthier Peter Donnelly
author_sort	Alexander I. Young
title	Multiple novel gene-by-environment interactions modify the effect of FTO variants on body mass index
title_short	Multiple novel gene-by-environment interactions modify the effect of FTO variants on body mass index
title_full	Multiple novel gene-by-environment interactions modify the effect of FTO variants on body mass index
title_fullStr	Multiple novel gene-by-environment interactions modify the effect of FTO variants on body mass index
title_full_unstemmed	Multiple novel gene-by-environment interactions modify the effect of FTO variants on body mass index
title_sort	multiple novel gene-by-environment interactions modify the effect of fto variants on body mass index
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/0d2d3074601b463b82844c074a61ce01
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Multiple novel gene-by-environment interactions modify the effect of FTO variants on body mass index

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