Modulation of polypeptide conformation through donor–acceptor transformation of side-chain hydrogen bonding ligands

Hydrogen bonding plays a major role in determining the tridimensional structure of biopolymers. Here, the authors show that control over a polypeptide conformation can be achieved by altering the donor-acceptor properties of side-chain triazole units via protonation-deprotonation.

Guardado en:
Detalles Bibliográficos
Autores principales: Ziyuan Song, Rachael A. Mansbach, Hua He, Kuo-Chih Shih, Ryan Baumgartner, Nan Zheng, Xiaochu Ba, Yinzhao Huang, Deepak Mani, Yun Liu, Yao Lin, Mu-Ping Nieh, Andrew L. Ferguson, Lichen Yin, Jianjun Cheng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/0d32e56919834d75b9cffc70076f783a
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:Hydrogen bonding plays a major role in determining the tridimensional structure of biopolymers. Here, the authors show that control over a polypeptide conformation can be achieved by altering the donor-acceptor properties of side-chain triazole units via protonation-deprotonation.