Modulation of polypeptide conformation through donor–acceptor transformation of side-chain hydrogen bonding ligands

Hydrogen bonding plays a major role in determining the tridimensional structure of biopolymers. Here, the authors show that control over a polypeptide conformation can be achieved by altering the donor-acceptor properties of side-chain triazole units via protonation-deprotonation.

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Autores principales:	Ziyuan Song, Rachael A. Mansbach, Hua He, Kuo-Chih Shih, Ryan Baumgartner, Nan Zheng, Xiaochu Ba, Yinzhao Huang, Deepak Mani, Yun Liu, Yao Lin, Mu-Ping Nieh, Andrew L. Ferguson, Lichen Yin, Jianjun Cheng
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0d32e56919834d75b9cffc70076f783a
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spelling	oai:doaj.org-article:0d32e56919834d75b9cffc70076f783a2021-12-02T10:48:09ZModulation of polypeptide conformation through donor–acceptor transformation of side-chain hydrogen bonding ligands10.1038/s41467-017-00079-52041-1723https://doaj.org/article/0d32e56919834d75b9cffc70076f783a2017-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00079-5https://doaj.org/toc/2041-1723Hydrogen bonding plays a major role in determining the tridimensional structure of biopolymers. Here, the authors show that control over a polypeptide conformation can be achieved by altering the donor-acceptor properties of side-chain triazole units via protonation-deprotonation.Ziyuan SongRachael A. MansbachHua HeKuo-Chih ShihRyan BaumgartnerNan ZhengXiaochu BaYinzhao HuangDeepak ManiYun LiuYao LinMu-Ping NiehAndrew L. FergusonLichen YinJianjun ChengNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ziyuan Song Rachael A. Mansbach Hua He Kuo-Chih Shih Ryan Baumgartner Nan Zheng Xiaochu Ba Yinzhao Huang Deepak Mani Yun Liu Yao Lin Mu-Ping Nieh Andrew L. Ferguson Lichen Yin Jianjun Cheng Modulation of polypeptide conformation through donor–acceptor transformation of side-chain hydrogen bonding ligands
description	Hydrogen bonding plays a major role in determining the tridimensional structure of biopolymers. Here, the authors show that control over a polypeptide conformation can be achieved by altering the donor-acceptor properties of side-chain triazole units via protonation-deprotonation.
format	article
author	Ziyuan Song Rachael A. Mansbach Hua He Kuo-Chih Shih Ryan Baumgartner Nan Zheng Xiaochu Ba Yinzhao Huang Deepak Mani Yun Liu Yao Lin Mu-Ping Nieh Andrew L. Ferguson Lichen Yin Jianjun Cheng
author_facet	Ziyuan Song Rachael A. Mansbach Hua He Kuo-Chih Shih Ryan Baumgartner Nan Zheng Xiaochu Ba Yinzhao Huang Deepak Mani Yun Liu Yao Lin Mu-Ping Nieh Andrew L. Ferguson Lichen Yin Jianjun Cheng
author_sort	Ziyuan Song
title	Modulation of polypeptide conformation through donor–acceptor transformation of side-chain hydrogen bonding ligands
title_short	Modulation of polypeptide conformation through donor–acceptor transformation of side-chain hydrogen bonding ligands
title_full	Modulation of polypeptide conformation through donor–acceptor transformation of side-chain hydrogen bonding ligands
title_fullStr	Modulation of polypeptide conformation through donor–acceptor transformation of side-chain hydrogen bonding ligands
title_full_unstemmed	Modulation of polypeptide conformation through donor–acceptor transformation of side-chain hydrogen bonding ligands
title_sort	modulation of polypeptide conformation through donor–acceptor transformation of side-chain hydrogen bonding ligands
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/0d32e56919834d75b9cffc70076f783a
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Modulation of polypeptide conformation through donor–acceptor transformation of side-chain hydrogen bonding ligands

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