Montreal Cognitive Assessment — Single Cutoff Achieves Screening Purpose

Pui Yu Yeung,1 LL Louise Wong,2 Chun Chung Chan,2 Cho Yiu Yung,3 LM Jess Leung,2 Yuen Yee Tam,3 Lap Nin Tang,3 Hiu Sze Li,3 Mei Ling Lau3 1Department of Medicine, Tung Wah Eastern Hospital, Causeway Bay, Hong Kong Special Administrative Region, People’s Republic of China; 2Private Practice...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Yeung PY, Wong LLL, Chan CC, Yung CY, Leung LMJ, Tam YY, Tang LN, Li HS, Lau ML
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	dementia hong kong mild cognitive impairment montreal cognitive assessment (moca) screening Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/0d3eeb001297477e8a02e7ebd466e4a0
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:0d3eeb001297477e8a02e7ebd466e4a0
record_format	dspace
spelling	oai:doaj.org-article:0d3eeb001297477e8a02e7ebd466e4a02021-12-02T12:10:22ZMontreal Cognitive Assessment — Single Cutoff Achieves Screening Purpose1178-2021https://doaj.org/article/0d3eeb001297477e8a02e7ebd466e4a02020-11-01T00:00:00Zhttps://www.dovepress.com/montreal-cognitive-assessment-mdash-single-cutoff-achieves-screening-p-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Pui Yu Yeung,1 LL Louise Wong,2 Chun Chung Chan,2 Cho Yiu Yung,3 LM Jess Leung,2 Yuen Yee Tam,3 Lap Nin Tang,3 Hiu Sze Li,3 Mei Ling Lau3 1Department of Medicine, Tung Wah Eastern Hospital, Causeway Bay, Hong Kong Special Administrative Region, People’s Republic of China; 2Private Practice, Tsim Sha Tsui and Central, Hong Kong Special Administrative Region, People’s Republic of China; 3Department of Medicine and Geriatrics, United Christian Hospital, Kwun Tong, Hong Kong Special Administrative Region, People’s Republic of ChinaCorrespondence: Pui Yu YeungDepartment of Medicine, Tung Wah Eastern Hospital, 19 Eastern Hospital Road, Causeway Bay, Hong Kong Special Administrative Region, People’s Republic of ChinaTel +852- 2162 6888Email yeunpy3@ha.org.hkBackground and Purpose: The study evaluated the performance between norm-derived age and education adjusted vs single cutoff scores of the Montreal Cognitive Assessment, Hong Kong version (HK-MoCA) in classifying cognitive impairment in Chinese older adults.Methods: Total scores of HK-MoCA were collected from 315 subjects (128 with dementia, 122 with mild cognitive impairment (MCI) and 65 normal) attending a public district hospital-based cognition clinic from 2012 to 2017. The HK-MoCA total scores were evaluated using different cutoffs. Norm-derived age and education adjusted cutoff scores were at 16th, 7th, and 2nd percentiles. Comparison was made with the single cutoff scores validated in a local study with 21/22 for MCI and 18/19 for dementia.Results: Single cutoff score of HK-MoCA differentiated MCI from normal with sensitivity of 0.861 and specificity of 0.723. To detect dementia, its sensitivity was 0.922, and specificity was 0.923. In identifying cognitive impairment, the sensitivity and specificity were 0.932 and 0.723, respectively. However, age and education adjusted cutoff scores achieved high specificities at all levels of cognitive impairment with trade-off of sensitivities. The accuracy of correctly classifying tested subjects into appropriate groups was 85.3% if single cutoff was used though the consistency between norm-derived cutoffs and expert diagnoses were only 59.0%, 54.2%, and 53.9% at 16th, 7th, and 2nd percentiles, respectively. The consistency decreased with older age and lower education level, and majority of misclassifications were false negatives.Conclusion: HK-MoCA is a convenient screening tool to detect cognitive impairment. Administration time is relatively short, and it has incorporated essential cognitive domains. Single cutoff scores with inherent simple education adjustment achieved screening purpose of mild cognitive impairment and dementia in Chinese older adults.Keywords: dementia, Hong Kong, mild cognitive impairment, Montreal Cognitive Assessment, MoCA, screeningYeung PYWong LLLChan CCYung CYLeung LMJTam YYTang LNLi HSLau MLDove Medical Pressarticledementiahong kongmild cognitive impairmentmontreal cognitive assessment (moca)screeningNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 16, Pp 2681-2687 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	dementia hong kong mild cognitive impairment montreal cognitive assessment (moca) screening Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	dementia hong kong mild cognitive impairment montreal cognitive assessment (moca) screening Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Yeung PY Wong LLL Chan CC Yung CY Leung LMJ Tam YY Tang LN Li HS Lau ML Montreal Cognitive Assessment — Single Cutoff Achieves Screening Purpose
description	Pui Yu Yeung,1 LL Louise Wong,2 Chun Chung Chan,2 Cho Yiu Yung,3 LM Jess Leung,2 Yuen Yee Tam,3 Lap Nin Tang,3 Hiu Sze Li,3 Mei Ling Lau3 1Department of Medicine, Tung Wah Eastern Hospital, Causeway Bay, Hong Kong Special Administrative Region, People’s Republic of China; 2Private Practice, Tsim Sha Tsui and Central, Hong Kong Special Administrative Region, People’s Republic of China; 3Department of Medicine and Geriatrics, United Christian Hospital, Kwun Tong, Hong Kong Special Administrative Region, People’s Republic of ChinaCorrespondence: Pui Yu YeungDepartment of Medicine, Tung Wah Eastern Hospital, 19 Eastern Hospital Road, Causeway Bay, Hong Kong Special Administrative Region, People’s Republic of ChinaTel +852- 2162 6888Email yeunpy3@ha.org.hkBackground and Purpose: The study evaluated the performance between norm-derived age and education adjusted vs single cutoff scores of the Montreal Cognitive Assessment, Hong Kong version (HK-MoCA) in classifying cognitive impairment in Chinese older adults.Methods: Total scores of HK-MoCA were collected from 315 subjects (128 with dementia, 122 with mild cognitive impairment (MCI) and 65 normal) attending a public district hospital-based cognition clinic from 2012 to 2017. The HK-MoCA total scores were evaluated using different cutoffs. Norm-derived age and education adjusted cutoff scores were at 16th, 7th, and 2nd percentiles. Comparison was made with the single cutoff scores validated in a local study with 21/22 for MCI and 18/19 for dementia.Results: Single cutoff score of HK-MoCA differentiated MCI from normal with sensitivity of 0.861 and specificity of 0.723. To detect dementia, its sensitivity was 0.922, and specificity was 0.923. In identifying cognitive impairment, the sensitivity and specificity were 0.932 and 0.723, respectively. However, age and education adjusted cutoff scores achieved high specificities at all levels of cognitive impairment with trade-off of sensitivities. The accuracy of correctly classifying tested subjects into appropriate groups was 85.3% if single cutoff was used though the consistency between norm-derived cutoffs and expert diagnoses were only 59.0%, 54.2%, and 53.9% at 16th, 7th, and 2nd percentiles, respectively. The consistency decreased with older age and lower education level, and majority of misclassifications were false negatives.Conclusion: HK-MoCA is a convenient screening tool to detect cognitive impairment. Administration time is relatively short, and it has incorporated essential cognitive domains. Single cutoff scores with inherent simple education adjustment achieved screening purpose of mild cognitive impairment and dementia in Chinese older adults.Keywords: dementia, Hong Kong, mild cognitive impairment, Montreal Cognitive Assessment, MoCA, screening
format	article
author	Yeung PY Wong LLL Chan CC Yung CY Leung LMJ Tam YY Tang LN Li HS Lau ML
author_facet	Yeung PY Wong LLL Chan CC Yung CY Leung LMJ Tam YY Tang LN Li HS Lau ML
author_sort	Yeung PY
title	Montreal Cognitive Assessment — Single Cutoff Achieves Screening Purpose
title_short	Montreal Cognitive Assessment — Single Cutoff Achieves Screening Purpose
title_full	Montreal Cognitive Assessment — Single Cutoff Achieves Screening Purpose
title_fullStr	Montreal Cognitive Assessment — Single Cutoff Achieves Screening Purpose
title_full_unstemmed	Montreal Cognitive Assessment — Single Cutoff Achieves Screening Purpose
title_sort	montreal cognitive assessment — single cutoff achieves screening purpose
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/0d3eeb001297477e8a02e7ebd466e4a0
work_keys_str_mv	AT yeungpy montrealcognitiveassessmentmdashsinglecutoffachievesscreeningpurpose AT wonglll montrealcognitiveassessmentmdashsinglecutoffachievesscreeningpurpose AT chancc montrealcognitiveassessmentmdashsinglecutoffachievesscreeningpurpose AT yungcy montrealcognitiveassessmentmdashsinglecutoffachievesscreeningpurpose AT leunglmj montrealcognitiveassessmentmdashsinglecutoffachievesscreeningpurpose AT tamyy montrealcognitiveassessmentmdashsinglecutoffachievesscreeningpurpose AT tangln montrealcognitiveassessmentmdashsinglecutoffachievesscreeningpurpose AT lihs montrealcognitiveassessmentmdashsinglecutoffachievesscreeningpurpose AT lauml montrealcognitiveassessmentmdashsinglecutoffachievesscreeningpurpose
_version_	1718394612901478400

Montreal Cognitive Assessment &mdash; Single Cutoff Achieves Screening Purpose

Ejemplares similares

Montreal Cognitive Assessment — Single Cutoff Achieves Screening Purpose