Reaction-diffusion hydrogels from urease enzyme particles for patterned coatings

Enzyme reaction networks can control the spatial and temporal formation of hydrogels. Here, inspired by biofilm formation, urease-containing particles create a propagating pH gradient which induces thiol-acrylate polymerization, with properties tuned by solution viscosity, particle dimensions, and s...

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Autores principales: Anthony Q. Mai, Tamás Bánsági, Annette F. Taylor, John A. Pojman
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/0d3fc377bd0f4451b65c80822c1e74c6
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Sumario:Enzyme reaction networks can control the spatial and temporal formation of hydrogels. Here, inspired by biofilm formation, urease-containing particles create a propagating pH gradient which induces thiol-acrylate polymerization, with properties tuned by solution viscosity, particle dimensions, and spatial configuration.