Sulphamoylated 2-methoxyestradiol analogues induce apoptosis in adenocarcinoma cell lines.
2-Methoxyestradiol (2ME2) is a naturally occurring estradiol metabolite which possesses antiproliferative, antiangiogenic and antitumor properties. However, due to its limited biological accessibility, synthetic analogues have been synthesized and tested in attempt to develop drugs with improved ora...
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Autores principales: | Michelle Visagie, Anne Theron, Thandi Mqoco, Warren Vieira, Renaud Prudent, Anne Martinez, Laurence Lafanechère, Annie Joubert |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/0d4768f1db5c42ceaeca946fa5dc627b |
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