Reprogramming of regulatory network using expression uncovers sex-specific gene regulation in Drosophila

For many applications knowledge of context-specific gene regulatory networks (GRNs) is desirable, but their inference remains a challenge. Here, the authors introduce a method for construction of context-specific GRNs, and apply it to construct sex-specific Drosophila GRNs.

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Autores principales:	Yijie Wang, Dong-Yeon Cho, Hangnoh Lee, Justin Fear, Brian Oliver, Teresa M. Przytycka
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0d494b9fcc90485dbc7949d2d0869433
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spelling	oai:doaj.org-article:0d494b9fcc90485dbc7949d2d08694332021-12-02T16:56:39ZReprogramming of regulatory network using expression uncovers sex-specific gene regulation in Drosophila10.1038/s41467-018-06382-z2041-1723https://doaj.org/article/0d494b9fcc90485dbc7949d2d08694332018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06382-zhttps://doaj.org/toc/2041-1723For many applications knowledge of context-specific gene regulatory networks (GRNs) is desirable, but their inference remains a challenge. Here, the authors introduce a method for construction of context-specific GRNs, and apply it to construct sex-specific Drosophila GRNs.Yijie WangDong-Yeon ChoHangnoh LeeJustin FearBrian OliverTeresa M. PrzytyckaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yijie Wang Dong-Yeon Cho Hangnoh Lee Justin Fear Brian Oliver Teresa M. Przytycka Reprogramming of regulatory network using expression uncovers sex-specific gene regulation in Drosophila
description	For many applications knowledge of context-specific gene regulatory networks (GRNs) is desirable, but their inference remains a challenge. Here, the authors introduce a method for construction of context-specific GRNs, and apply it to construct sex-specific Drosophila GRNs.
format	article
author	Yijie Wang Dong-Yeon Cho Hangnoh Lee Justin Fear Brian Oliver Teresa M. Przytycka
author_facet	Yijie Wang Dong-Yeon Cho Hangnoh Lee Justin Fear Brian Oliver Teresa M. Przytycka
author_sort	Yijie Wang
title	Reprogramming of regulatory network using expression uncovers sex-specific gene regulation in Drosophila
title_short	Reprogramming of regulatory network using expression uncovers sex-specific gene regulation in Drosophila
title_full	Reprogramming of regulatory network using expression uncovers sex-specific gene regulation in Drosophila
title_fullStr	Reprogramming of regulatory network using expression uncovers sex-specific gene regulation in Drosophila
title_full_unstemmed	Reprogramming of regulatory network using expression uncovers sex-specific gene regulation in Drosophila
title_sort	reprogramming of regulatory network using expression uncovers sex-specific gene regulation in drosophila
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/0d494b9fcc90485dbc7949d2d0869433
work_keys_str_mv	AT yijiewang reprogrammingofregulatorynetworkusingexpressionuncoverssexspecificgeneregulationindrosophila AT dongyeoncho reprogrammingofregulatorynetworkusingexpressionuncoverssexspecificgeneregulationindrosophila AT hangnohlee reprogrammingofregulatorynetworkusingexpressionuncoverssexspecificgeneregulationindrosophila AT justinfear reprogrammingofregulatorynetworkusingexpressionuncoverssexspecificgeneregulationindrosophila AT brianoliver reprogrammingofregulatorynetworkusingexpressionuncoverssexspecificgeneregulationindrosophila AT teresamprzytycka reprogrammingofregulatorynetworkusingexpressionuncoverssexspecificgeneregulationindrosophila
_version_	1718382723246063616

Reprogramming of regulatory network using expression uncovers sex-specific gene regulation in Drosophila

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