Bi- and uniciliated ependymal cells define continuous floor-plate-derived tanycytic territories

Ependymal cells lining the adult brain ventricles are comprised of multiciliated cells and a rare subpopulation with two cilia (E2 cells) whose origin and function remain unknown. Here the authors find E2 cells in the 3rd ventricle of mice and humans, along with a third ependymal cell type with only...

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Autores principales: Zaman Mirzadeh, Yael Kusne, Maria Duran-Moreno, Elaine Cabrales, Sara Gil-Perotin, Christian Ortiz, Bin Chen, Jose Manuel Garcia-Verdugo, Nader Sanai, Arturo Alvarez-Buylla
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/0d4d22cbb44b43e885381003940754c8
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spelling oai:doaj.org-article:0d4d22cbb44b43e885381003940754c82021-12-02T14:40:57ZBi- and uniciliated ependymal cells define continuous floor-plate-derived tanycytic territories10.1038/ncomms137592041-1723https://doaj.org/article/0d4d22cbb44b43e885381003940754c82017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms13759https://doaj.org/toc/2041-1723Ependymal cells lining the adult brain ventricles are comprised of multiciliated cells and a rare subpopulation with two cilia (E2 cells) whose origin and function remain unknown. Here the authors find E2 cells in the 3rd ventricle of mice and humans, along with a third ependymal cell type with only a primary cilium, and provide details of their marker profile and developmental origins.Zaman MirzadehYael KusneMaria Duran-MorenoElaine CabralesSara Gil-PerotinChristian OrtizBin ChenJose Manuel Garcia-VerdugoNader SanaiArturo Alvarez-BuyllaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Zaman Mirzadeh
Yael Kusne
Maria Duran-Moreno
Elaine Cabrales
Sara Gil-Perotin
Christian Ortiz
Bin Chen
Jose Manuel Garcia-Verdugo
Nader Sanai
Arturo Alvarez-Buylla
Bi- and uniciliated ependymal cells define continuous floor-plate-derived tanycytic territories
description Ependymal cells lining the adult brain ventricles are comprised of multiciliated cells and a rare subpopulation with two cilia (E2 cells) whose origin and function remain unknown. Here the authors find E2 cells in the 3rd ventricle of mice and humans, along with a third ependymal cell type with only a primary cilium, and provide details of their marker profile and developmental origins.
format article
author Zaman Mirzadeh
Yael Kusne
Maria Duran-Moreno
Elaine Cabrales
Sara Gil-Perotin
Christian Ortiz
Bin Chen
Jose Manuel Garcia-Verdugo
Nader Sanai
Arturo Alvarez-Buylla
author_facet Zaman Mirzadeh
Yael Kusne
Maria Duran-Moreno
Elaine Cabrales
Sara Gil-Perotin
Christian Ortiz
Bin Chen
Jose Manuel Garcia-Verdugo
Nader Sanai
Arturo Alvarez-Buylla
author_sort Zaman Mirzadeh
title Bi- and uniciliated ependymal cells define continuous floor-plate-derived tanycytic territories
title_short Bi- and uniciliated ependymal cells define continuous floor-plate-derived tanycytic territories
title_full Bi- and uniciliated ependymal cells define continuous floor-plate-derived tanycytic territories
title_fullStr Bi- and uniciliated ependymal cells define continuous floor-plate-derived tanycytic territories
title_full_unstemmed Bi- and uniciliated ependymal cells define continuous floor-plate-derived tanycytic territories
title_sort bi- and uniciliated ependymal cells define continuous floor-plate-derived tanycytic territories
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/0d4d22cbb44b43e885381003940754c8
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