Genomic regression analysis of coordinated expression

Somatic copy number alterations (SCNA) can confound gene co-expression analysis in cancers. Here the authors develop a method to remove the effects of SCNA in co-expression analysis, improving the analysis of network rewiring in cancer, and provide a database with adjusted data from TCGA.

Guardado en:

Detalles Bibliográficos
Autores principales:	Ling Cai, Qiwei Li, Yi Du, Jonghyun Yun, Yang Xie, Ralph J. DeBerardinis, Guanghua Xiao
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0d5b683757f54cdc82e68c7e1888eb8d
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:0d5b683757f54cdc82e68c7e1888eb8d
record_format	dspace
spelling	oai:doaj.org-article:0d5b683757f54cdc82e68c7e1888eb8d2021-12-02T15:38:42ZGenomic regression analysis of coordinated expression10.1038/s41467-017-02181-02041-1723https://doaj.org/article/0d5b683757f54cdc82e68c7e1888eb8d2017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02181-0https://doaj.org/toc/2041-1723Somatic copy number alterations (SCNA) can confound gene co-expression analysis in cancers. Here the authors develop a method to remove the effects of SCNA in co-expression analysis, improving the analysis of network rewiring in cancer, and provide a database with adjusted data from TCGA.Ling CaiQiwei LiYi DuJonghyun YunYang XieRalph J. DeBerardinisGuanghua XiaoNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ling Cai Qiwei Li Yi Du Jonghyun Yun Yang Xie Ralph J. DeBerardinis Guanghua Xiao Genomic regression analysis of coordinated expression
description	Somatic copy number alterations (SCNA) can confound gene co-expression analysis in cancers. Here the authors develop a method to remove the effects of SCNA in co-expression analysis, improving the analysis of network rewiring in cancer, and provide a database with adjusted data from TCGA.
format	article
author	Ling Cai Qiwei Li Yi Du Jonghyun Yun Yang Xie Ralph J. DeBerardinis Guanghua Xiao
author_facet	Ling Cai Qiwei Li Yi Du Jonghyun Yun Yang Xie Ralph J. DeBerardinis Guanghua Xiao
author_sort	Ling Cai
title	Genomic regression analysis of coordinated expression
title_short	Genomic regression analysis of coordinated expression
title_full	Genomic regression analysis of coordinated expression
title_fullStr	Genomic regression analysis of coordinated expression
title_full_unstemmed	Genomic regression analysis of coordinated expression
title_sort	genomic regression analysis of coordinated expression
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/0d5b683757f54cdc82e68c7e1888eb8d
work_keys_str_mv	AT lingcai genomicregressionanalysisofcoordinatedexpression AT qiweili genomicregressionanalysisofcoordinatedexpression AT yidu genomicregressionanalysisofcoordinatedexpression AT jonghyunyun genomicregressionanalysisofcoordinatedexpression AT yangxie genomicregressionanalysisofcoordinatedexpression AT ralphjdeberardinis genomicregressionanalysisofcoordinatedexpression AT guanghuaxiao genomicregressionanalysisofcoordinatedexpression
_version_	1718386093528711168

Genomic regression analysis of coordinated expression

Ejemplares similares