The sigma-1 receptor modulates methamphetamine dysregulation of dopamine neurotransmission
The dopamine transporter (DAT), a regulator of dopamine homeostasis in the brain, and sigma-1 receptor (σ1R), an endoplasmic reticulum membrane protein, are both implicated in drug addiction. In this work, the authors investigate how σ1R modulates DAT response to methamphetamine.
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Nature Portfolio
2017
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oai:doaj.org-article:0d6245895b2e42a080e1391355fcd9ae2021-12-02T14:42:18ZThe sigma-1 receptor modulates methamphetamine dysregulation of dopamine neurotransmission10.1038/s41467-017-02087-x2041-1723https://doaj.org/article/0d6245895b2e42a080e1391355fcd9ae2017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02087-xhttps://doaj.org/toc/2041-1723The dopamine transporter (DAT), a regulator of dopamine homeostasis in the brain, and sigma-1 receptor (σ1R), an endoplasmic reticulum membrane protein, are both implicated in drug addiction. In this work, the authors investigate how σ1R modulates DAT response to methamphetamine.Danielle O. SamboMin LinAnthony OwensJoseph J. LebowitzBen RichardsonDarin A. JagnarineMadhur ShettyMeghan RodriquezTaiwo AlongeMishaal AliJonathan KatzLong YanMarcelo FeboL. Keith HenryAdriaan W. BruijnzeelLynette DawsHabibeh KhoshboueiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-18 (2017) |
| institution |
DOAJ |
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DOAJ |
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EN |
| topic |
Science Q |
| spellingShingle |
Science Q Danielle O. Sambo Min Lin Anthony Owens Joseph J. Lebowitz Ben Richardson Darin A. Jagnarine Madhur Shetty Meghan Rodriquez Taiwo Alonge Mishaal Ali Jonathan Katz Long Yan Marcelo Febo L. Keith Henry Adriaan W. Bruijnzeel Lynette Daws Habibeh Khoshbouei The sigma-1 receptor modulates methamphetamine dysregulation of dopamine neurotransmission |
| description |
The dopamine transporter (DAT), a regulator of dopamine homeostasis in the brain, and sigma-1 receptor (σ1R), an endoplasmic reticulum membrane protein, are both implicated in drug addiction. In this work, the authors investigate how σ1R modulates DAT response to methamphetamine. |
| format |
article |
| author |
Danielle O. Sambo Min Lin Anthony Owens Joseph J. Lebowitz Ben Richardson Darin A. Jagnarine Madhur Shetty Meghan Rodriquez Taiwo Alonge Mishaal Ali Jonathan Katz Long Yan Marcelo Febo L. Keith Henry Adriaan W. Bruijnzeel Lynette Daws Habibeh Khoshbouei |
| author_facet |
Danielle O. Sambo Min Lin Anthony Owens Joseph J. Lebowitz Ben Richardson Darin A. Jagnarine Madhur Shetty Meghan Rodriquez Taiwo Alonge Mishaal Ali Jonathan Katz Long Yan Marcelo Febo L. Keith Henry Adriaan W. Bruijnzeel Lynette Daws Habibeh Khoshbouei |
| author_sort |
Danielle O. Sambo |
| title |
The sigma-1 receptor modulates methamphetamine dysregulation of dopamine neurotransmission |
| title_short |
The sigma-1 receptor modulates methamphetamine dysregulation of dopamine neurotransmission |
| title_full |
The sigma-1 receptor modulates methamphetamine dysregulation of dopamine neurotransmission |
| title_fullStr |
The sigma-1 receptor modulates methamphetamine dysregulation of dopamine neurotransmission |
| title_full_unstemmed |
The sigma-1 receptor modulates methamphetamine dysregulation of dopamine neurotransmission |
| title_sort |
sigma-1 receptor modulates methamphetamine dysregulation of dopamine neurotransmission |
| publisher |
Nature Portfolio |
| publishDate |
2017 |
| url |
https://doaj.org/article/0d6245895b2e42a080e1391355fcd9ae |
| work_keys_str_mv |
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