ReacKnock: identifying reaction deletion strategies for microbial strain optimization based on genome-scale metabolic network.

Gene knockout has been used as a common strategy to improve microbial strains for producing chemicals. Several algorithms are available to predict the target reactions to be deleted. Most of them apply mixed integer bi-level linear programming (MIBLP) based on metabolic networks, and use duality the...

Full description

Saved in:
Bibliographic Details
Main Authors: Zixiang Xu, Ping Zheng, Jibin Sun, Yanhe Ma
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
R
Q
Online Access:https://doaj.org/article/0d683363b0124fb6a9cc32b118e7a33a
Tags: Add Tag
No Tags, Be the first to tag this record!