ReacKnock: identifying reaction deletion strategies for microbial strain optimization based on genome-scale metabolic network.
Gene knockout has been used as a common strategy to improve microbial strains for producing chemicals. Several algorithms are available to predict the target reactions to be deleted. Most of them apply mixed integer bi-level linear programming (MIBLP) based on metabolic networks, and use duality the...
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Main Authors: | , , , |
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Format: | article |
Language: | EN |
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Public Library of Science (PLoS)
2013
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Online Access: | https://doaj.org/article/0d683363b0124fb6a9cc32b118e7a33a |
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