Effect of selection bias on two sample summary data based Mendelian randomization

Abstract Mendelian randomization (MR) is becoming more and more popular for inferring causal relationship between an exposure and a trait. Typically, instrument SNPs are selected from an exposure GWAS based on their summary statistics and the same summary statistics on the selected SNPs are used for...

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Bibliographic Details
Main Authors: Kai Wang, Shizhong Han
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/0d6b81de6c9f42d9a9fde154769608a2
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