Viral Rebound Kinetics Correlate with Distinct HIV Antibody Features

Plasma viremia reoccurs in most HIV-infected individuals once antiretroviral therapy is interrupted, and interindividual differences in the kinetics of viral rebound have been associated with virological and immunological factors. Antibody features, including Fc functionality and Fc glycosylation,...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Yannic C. Bartsch, Carolin Loos, Evan Rossignol, Jesse M. Fajnzylber, Dansu Yuan, Anchalee Avihingsanon, Sasiwimol Ubolyam, Thidarat Jupimai, Bernard Hirschel, Jintanat Ananworanich, Douglas A. Lauffenburger, Jonathan Z. Li, Galit Alter, Boris Julg
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://doaj.org/article/0d79010a8b104f799629b76d4e2c691d
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:Plasma viremia reoccurs in most HIV-infected individuals once antiretroviral therapy is interrupted, and interindividual differences in the kinetics of viral rebound have been associated with virological and immunological factors. Antibody features, including Fc functionality and Fc glycosylation, have been identified as sensitive surrogates for disease activity in multiple diseases.