Viral Rebound Kinetics Correlate with Distinct HIV Antibody Features

Plasma viremia reoccurs in most HIV-infected individuals once antiretroviral therapy is interrupted, and interindividual differences in the kinetics of viral rebound have been associated with virological and immunological factors. Antibody features, including Fc functionality and Fc glycosylation,...

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Autores principales: Yannic C. Bartsch, Carolin Loos, Evan Rossignol, Jesse M. Fajnzylber, Dansu Yuan, Anchalee Avihingsanon, Sasiwimol Ubolyam, Thidarat Jupimai, Bernard Hirschel, Jintanat Ananworanich, Douglas A. Lauffenburger, Jonathan Z. Li, Galit Alter, Boris Julg
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Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/0d79010a8b104f799629b76d4e2c691d
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spelling oai:doaj.org-article:0d79010a8b104f799629b76d4e2c691d2021-11-03T18:56:09ZViral Rebound Kinetics Correlate with Distinct HIV Antibody Features2150-751110.1128/mBio.00170-21https://doaj.org/article/0d79010a8b104f799629b76d4e2c691d2021-04-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00170-21https://doaj.org/toc/2150-7511 Plasma viremia reoccurs in most HIV-infected individuals once antiretroviral therapy is interrupted, and interindividual differences in the kinetics of viral rebound have been associated with virological and immunological factors. Antibody features, including Fc functionality and Fc glycosylation, have been identified as sensitive surrogates for disease activity in multiple diseases.Yannic C. BartschCarolin LoosEvan RossignolJesse M. FajnzylberDansu YuanAnchalee AvihingsanonSasiwimol UbolyamThidarat JupimaiBernard HirschelJintanat AnanworanichDouglas A. LauffenburgerJonathan Z. LiGalit AlterBoris JulgAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 2 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Yannic C. Bartsch
Carolin Loos
Evan Rossignol
Jesse M. Fajnzylber
Dansu Yuan
Anchalee Avihingsanon
Sasiwimol Ubolyam
Thidarat Jupimai
Bernard Hirschel
Jintanat Ananworanich
Douglas A. Lauffenburger
Jonathan Z. Li
Galit Alter
Boris Julg
Viral Rebound Kinetics Correlate with Distinct HIV Antibody Features
description Plasma viremia reoccurs in most HIV-infected individuals once antiretroviral therapy is interrupted, and interindividual differences in the kinetics of viral rebound have been associated with virological and immunological factors. Antibody features, including Fc functionality and Fc glycosylation, have been identified as sensitive surrogates for disease activity in multiple diseases.
format article
author Yannic C. Bartsch
Carolin Loos
Evan Rossignol
Jesse M. Fajnzylber
Dansu Yuan
Anchalee Avihingsanon
Sasiwimol Ubolyam
Thidarat Jupimai
Bernard Hirschel
Jintanat Ananworanich
Douglas A. Lauffenburger
Jonathan Z. Li
Galit Alter
Boris Julg
author_facet Yannic C. Bartsch
Carolin Loos
Evan Rossignol
Jesse M. Fajnzylber
Dansu Yuan
Anchalee Avihingsanon
Sasiwimol Ubolyam
Thidarat Jupimai
Bernard Hirschel
Jintanat Ananworanich
Douglas A. Lauffenburger
Jonathan Z. Li
Galit Alter
Boris Julg
author_sort Yannic C. Bartsch
title Viral Rebound Kinetics Correlate with Distinct HIV Antibody Features
title_short Viral Rebound Kinetics Correlate with Distinct HIV Antibody Features
title_full Viral Rebound Kinetics Correlate with Distinct HIV Antibody Features
title_fullStr Viral Rebound Kinetics Correlate with Distinct HIV Antibody Features
title_full_unstemmed Viral Rebound Kinetics Correlate with Distinct HIV Antibody Features
title_sort viral rebound kinetics correlate with distinct hiv antibody features
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/0d79010a8b104f799629b76d4e2c691d
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