In utero exposure to endogenous maternal polyclonal anti-Caspr2 antibody leads to behavioral abnormalities resembling autism spectrum disorder in male mice
Abstract The concept that exposure in utero to maternal anti-brain antibodies contributes to the development of autism spectrum disorders (ASD) has been entertained for over a decade. We determined that antibodies targeting Caspr2 are present at high frequency in mothers with brain-reactive serology...
Guardado en:
Autores principales: | Ciara Bagnall-Moreau, Patricio T. Huerta, Davide Comoletti, Andrea La-Bella, Roseann Berlin, Chunfang Zhao, Bruce T. Volpe, Betty Diamond, Lior Brimberg |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/0d79b86102654d0993d2e8b06b7ea1de |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Caspr1 is a host receptor for meningitis-causing Escherichia coli
por: Wei-Dong Zhao, et al.
Publicado: (2018) -
Nogo receptor 1 regulates Caspr distribution at axo-glial units in the central nervous system
por: Jae Young Lee, et al.
Publicado: (2017) -
Case Report: Prominent Brainstem Involvement in Two Patients With Anti-CASPR2 Antibody-Associated Autoimmune Encephalitis
por: Pei Liu, et al.
Publicado: (2021) -
ABZYME ACTIVITY OF POLYCLONAL IMMUNOGLOBULINS IN SPONDYLOARTHROPATHIES
por: E. V. Kunder
Publicado: (2014) -
Polyclonal light chains in cerebrovascular disease
por: Patrizia Fiori, et al.
Publicado: (2010)