Opponent control of behavioral reinforcement by inhibitory and excitatory projections from the ventral pallidum

The ventral palladium (VP) is involved in reward and contains mostly GABAergic neurons, but also glutamatergic neurons. Here, the authors characterize glutamatergic VP neurons and show that glutamatergic versus GABAergic projections play roles in avoidance and reinforcement, respectively.

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Autores principales: Lauren Faget, Vivien Zell, Elizabeth Souter, Adam McPherson, Reed Ressler, Navarre Gutierrez-Reed, Ji Hoon Yoo, Davide Dulcis, Thomas S. Hnasko
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/0d8105c30e874e1aa7d317c939b86bc1
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Sumario:The ventral palladium (VP) is involved in reward and contains mostly GABAergic neurons, but also glutamatergic neurons. Here, the authors characterize glutamatergic VP neurons and show that glutamatergic versus GABAergic projections play roles in avoidance and reinforcement, respectively.