Structure–function studies of ultrahigh molecular weight isoprenes provide key insights into their biosynthesis

Kajiura and Yoshizawa et al. identify three new prenyltransferases in the tree Eucommia ulmoides that synthesize exceptionally high molecular weight trans-1,4-polyisoprene (TPI). Through crystal structure and mutational analyses, they identify key residues required for TPI synthesis and reveal its f...

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Autores principales:	Hiroyuki Kajiura, Takuya Yoshizawa, Yuji Tokumoto, Nobuaki Suzuki, Shinya Takeno, Kanokwan Jumtee Takeno, Takuya Yamashita, Shun-ichi Tanaka, Yoshinobu Kaneko, Kazuhito Fujiyama, Hiroyoshi Matsumura, Yoshihisa Nakazawa
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/0d8d4e20f5c54474bdd6cf4c60bfba98
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spelling	oai:doaj.org-article:0d8d4e20f5c54474bdd6cf4c60bfba982021-12-02T14:03:56ZStructure–function studies of ultrahigh molecular weight isoprenes provide key insights into their biosynthesis10.1038/s42003-021-01739-52399-3642https://doaj.org/article/0d8d4e20f5c54474bdd6cf4c60bfba982021-02-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01739-5https://doaj.org/toc/2399-3642Kajiura and Yoshizawa et al. identify three new prenyltransferases in the tree Eucommia ulmoides that synthesize exceptionally high molecular weight trans-1,4-polyisoprene (TPI). Through crystal structure and mutational analyses, they identify key residues required for TPI synthesis and reveal its functional importance in seed development.Hiroyuki KajiuraTakuya YoshizawaYuji TokumotoNobuaki SuzukiShinya TakenoKanokwan Jumtee TakenoTakuya YamashitaShun-ichi TanakaYoshinobu KanekoKazuhito FujiyamaHiroyoshi MatsumuraYoshihisa NakazawaNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Hiroyuki Kajiura Takuya Yoshizawa Yuji Tokumoto Nobuaki Suzuki Shinya Takeno Kanokwan Jumtee Takeno Takuya Yamashita Shun-ichi Tanaka Yoshinobu Kaneko Kazuhito Fujiyama Hiroyoshi Matsumura Yoshihisa Nakazawa Structure–function studies of ultrahigh molecular weight isoprenes provide key insights into their biosynthesis
description	Kajiura and Yoshizawa et al. identify three new prenyltransferases in the tree Eucommia ulmoides that synthesize exceptionally high molecular weight trans-1,4-polyisoprene (TPI). Through crystal structure and mutational analyses, they identify key residues required for TPI synthesis and reveal its functional importance in seed development.
format	article
author	Hiroyuki Kajiura Takuya Yoshizawa Yuji Tokumoto Nobuaki Suzuki Shinya Takeno Kanokwan Jumtee Takeno Takuya Yamashita Shun-ichi Tanaka Yoshinobu Kaneko Kazuhito Fujiyama Hiroyoshi Matsumura Yoshihisa Nakazawa
author_facet	Hiroyuki Kajiura Takuya Yoshizawa Yuji Tokumoto Nobuaki Suzuki Shinya Takeno Kanokwan Jumtee Takeno Takuya Yamashita Shun-ichi Tanaka Yoshinobu Kaneko Kazuhito Fujiyama Hiroyoshi Matsumura Yoshihisa Nakazawa
author_sort	Hiroyuki Kajiura
title	Structure–function studies of ultrahigh molecular weight isoprenes provide key insights into their biosynthesis
title_short	Structure–function studies of ultrahigh molecular weight isoprenes provide key insights into their biosynthesis
title_full	Structure–function studies of ultrahigh molecular weight isoprenes provide key insights into their biosynthesis
title_fullStr	Structure–function studies of ultrahigh molecular weight isoprenes provide key insights into their biosynthesis
title_full_unstemmed	Structure–function studies of ultrahigh molecular weight isoprenes provide key insights into their biosynthesis
title_sort	structure–function studies of ultrahigh molecular weight isoprenes provide key insights into their biosynthesis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0d8d4e20f5c54474bdd6cf4c60bfba98
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Structure–function studies of ultrahigh molecular weight isoprenes provide key insights into their biosynthesis

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