Fast alignment and preprocessing of chromatin profiles with Chromap

As studies continue sequencing with deeper coverage, computational processing of these profiles has become increasingly resource consuming. Here the authors designed an efficient computational method called Chromap to align and preprocess high throughput sequencing data from chromatin profiling tech...

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Autores principales:	Haowen Zhang, Li Song, Xiaotao Wang, Haoyu Cheng, Chenfei Wang, Clifford A. Meyer, Tao Liu, Ming Tang, Srinivas Aluru, Feng Yue, X. Shirley Liu, Heng Li
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0d8e074a07ed48daaa24e1ce45413134
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spelling	oai:doaj.org-article:0d8e074a07ed48daaa24e1ce454131342021-11-14T12:34:47ZFast alignment and preprocessing of chromatin profiles with Chromap10.1038/s41467-021-26865-w2041-1723https://doaj.org/article/0d8e074a07ed48daaa24e1ce454131342021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26865-whttps://doaj.org/toc/2041-1723As studies continue sequencing with deeper coverage, computational processing of these profiles has become increasingly resource consuming. Here the authors designed an efficient computational method called Chromap to align and preprocess high throughput sequencing data from chromatin profiling techniques, including ChIP-seq, Hi-C, or scATAC-seq, with a major decrease in runtime.Haowen ZhangLi SongXiaotao WangHaoyu ChengChenfei WangClifford A. MeyerTao LiuMing TangSrinivas AluruFeng YueX. Shirley LiuHeng LiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-6 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Haowen Zhang Li Song Xiaotao Wang Haoyu Cheng Chenfei Wang Clifford A. Meyer Tao Liu Ming Tang Srinivas Aluru Feng Yue X. Shirley Liu Heng Li Fast alignment and preprocessing of chromatin profiles with Chromap
description	As studies continue sequencing with deeper coverage, computational processing of these profiles has become increasingly resource consuming. Here the authors designed an efficient computational method called Chromap to align and preprocess high throughput sequencing data from chromatin profiling techniques, including ChIP-seq, Hi-C, or scATAC-seq, with a major decrease in runtime.
format	article
author	Haowen Zhang Li Song Xiaotao Wang Haoyu Cheng Chenfei Wang Clifford A. Meyer Tao Liu Ming Tang Srinivas Aluru Feng Yue X. Shirley Liu Heng Li
author_facet	Haowen Zhang Li Song Xiaotao Wang Haoyu Cheng Chenfei Wang Clifford A. Meyer Tao Liu Ming Tang Srinivas Aluru Feng Yue X. Shirley Liu Heng Li
author_sort	Haowen Zhang
title	Fast alignment and preprocessing of chromatin profiles with Chromap
title_short	Fast alignment and preprocessing of chromatin profiles with Chromap
title_full	Fast alignment and preprocessing of chromatin profiles with Chromap
title_fullStr	Fast alignment and preprocessing of chromatin profiles with Chromap
title_full_unstemmed	Fast alignment and preprocessing of chromatin profiles with Chromap
title_sort	fast alignment and preprocessing of chromatin profiles with chromap
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0d8e074a07ed48daaa24e1ce45413134
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Fast alignment and preprocessing of chromatin profiles with Chromap

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