Relationship between Short-Range and Homotopic Long-Range Resting State Functional Connectivity in Temporal Lobes in Autism Spectrum Disorder

To investigate the relationship between short-range and homotopic long-range resting state functional connectivity (RSFC) in children with autism spectrum disorder (ASD) and typically developing (TD) children, we analyzed functional near-infrared spectroscopy (fNIRS) RSFC in 25 children with ASD and...

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Autores principales:	Xiaoyin Wu, Fang Lin, Weiting Sun, Tingzhen Zhang, Huiwen Sun, Jun Li
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	autism spectrum disorder (ASD) functional near-infrared spectroscopy (fNIRS) resting-state functional connectivity (RSFC) short-range RSFC long-range RSFC Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
Acceso en línea:	https://doaj.org/article/0d90fe8cebc04783997b94ab69ad386f
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spelling	oai:doaj.org-article:0d90fe8cebc04783997b94ab69ad386f2021-11-25T16:57:55ZRelationship between Short-Range and Homotopic Long-Range Resting State Functional Connectivity in Temporal Lobes in Autism Spectrum Disorder10.3390/brainsci111114672076-3425https://doaj.org/article/0d90fe8cebc04783997b94ab69ad386f2021-11-01T00:00:00Zhttps://www.mdpi.com/2076-3425/11/11/1467https://doaj.org/toc/2076-3425To investigate the relationship between short-range and homotopic long-range resting state functional connectivity (RSFC) in children with autism spectrum disorder (ASD) and typically developing (TD) children, we analyzed functional near-infrared spectroscopy (fNIRS) RSFC in 25 children with ASD and 22 age-matched TD children. The resting state fNIRS signals, including spontaneous fluctuations in the oxygenated hemoglobin (HbO<sub>2</sub>) and deoxygenated hemoglobin (Hb) concentrations, were recorded from the bilateral temporal lobes. We found that (1) there was no difference in the short-range RSFC between the left and right hemisphere in either ASD or TD group; (2) both the short-range and homotopic long-range RSFC were weaker in the ASD than TD group; and (3) the short-range RSFC was stronger than the homotopic long-range RSFC in the ASD group, whereas no such difference was observed in the TD group. These observations might be helpful for a better understanding of the underlying cortical mechanism in ASD.Xiaoyin WuFang LinWeiting SunTingzhen ZhangHuiwen SunJun LiMDPI AGarticleautism spectrum disorder (ASD)functional near-infrared spectroscopy (fNIRS)resting-state functional connectivity (RSFC)short-range RSFClong-range RSFCNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571ENBrain Sciences, Vol 11, Iss 1467, p 1467 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	autism spectrum disorder (ASD) functional near-infrared spectroscopy (fNIRS) resting-state functional connectivity (RSFC) short-range RSFC long-range RSFC Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
spellingShingle	autism spectrum disorder (ASD) functional near-infrared spectroscopy (fNIRS) resting-state functional connectivity (RSFC) short-range RSFC long-range RSFC Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Xiaoyin Wu Fang Lin Weiting Sun Tingzhen Zhang Huiwen Sun Jun Li Relationship between Short-Range and Homotopic Long-Range Resting State Functional Connectivity in Temporal Lobes in Autism Spectrum Disorder
description	To investigate the relationship between short-range and homotopic long-range resting state functional connectivity (RSFC) in children with autism spectrum disorder (ASD) and typically developing (TD) children, we analyzed functional near-infrared spectroscopy (fNIRS) RSFC in 25 children with ASD and 22 age-matched TD children. The resting state fNIRS signals, including spontaneous fluctuations in the oxygenated hemoglobin (HbO<sub>2</sub>) and deoxygenated hemoglobin (Hb) concentrations, were recorded from the bilateral temporal lobes. We found that (1) there was no difference in the short-range RSFC between the left and right hemisphere in either ASD or TD group; (2) both the short-range and homotopic long-range RSFC were weaker in the ASD than TD group; and (3) the short-range RSFC was stronger than the homotopic long-range RSFC in the ASD group, whereas no such difference was observed in the TD group. These observations might be helpful for a better understanding of the underlying cortical mechanism in ASD.
format	article
author	Xiaoyin Wu Fang Lin Weiting Sun Tingzhen Zhang Huiwen Sun Jun Li
author_facet	Xiaoyin Wu Fang Lin Weiting Sun Tingzhen Zhang Huiwen Sun Jun Li
author_sort	Xiaoyin Wu
title	Relationship between Short-Range and Homotopic Long-Range Resting State Functional Connectivity in Temporal Lobes in Autism Spectrum Disorder
title_short	Relationship between Short-Range and Homotopic Long-Range Resting State Functional Connectivity in Temporal Lobes in Autism Spectrum Disorder
title_full	Relationship between Short-Range and Homotopic Long-Range Resting State Functional Connectivity in Temporal Lobes in Autism Spectrum Disorder
title_fullStr	Relationship between Short-Range and Homotopic Long-Range Resting State Functional Connectivity in Temporal Lobes in Autism Spectrum Disorder
title_full_unstemmed	Relationship between Short-Range and Homotopic Long-Range Resting State Functional Connectivity in Temporal Lobes in Autism Spectrum Disorder
title_sort	relationship between short-range and homotopic long-range resting state functional connectivity in temporal lobes in autism spectrum disorder
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/0d90fe8cebc04783997b94ab69ad386f
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Relationship between Short-Range and Homotopic Long-Range Resting State Functional Connectivity in Temporal Lobes in Autism Spectrum Disorder

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