Phosphoric acid-catalyzed atroposelective construction of axially chiral arylpyrroles
Axially chiral arylpyrroles are structural motifs often found in natural and medicinal products. Here, the authors report the atroposelective synthesis of axially chiral arylpyrrole derivatives, which proved to be efficient chiral ligands for asymmetric catalysis, through desymmetrization and kineti...
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Nature Portfolio
2019
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oai:doaj.org-article:0d9153db87224e71999d97ccc3260a2f2021-12-02T17:31:53ZPhosphoric acid-catalyzed atroposelective construction of axially chiral arylpyrroles10.1038/s41467-019-08447-z2041-1723https://doaj.org/article/0d9153db87224e71999d97ccc3260a2f2019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08447-zhttps://doaj.org/toc/2041-1723Axially chiral arylpyrroles are structural motifs often found in natural and medicinal products. Here, the authors report the atroposelective synthesis of axially chiral arylpyrrole derivatives, which proved to be efficient chiral ligands for asymmetric catalysis, through desymmetrization and kinetic resolution.Lei ZhangShao-Hua XiangJun (Joelle) WangJian XiaoJun-Qi WangBin TanNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019) |
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Science Q Lei Zhang Shao-Hua Xiang Jun (Joelle) Wang Jian Xiao Jun-Qi Wang Bin Tan Phosphoric acid-catalyzed atroposelective construction of axially chiral arylpyrroles |
description |
Axially chiral arylpyrroles are structural motifs often found in natural and medicinal products. Here, the authors report the atroposelective synthesis of axially chiral arylpyrrole derivatives, which proved to be efficient chiral ligands for asymmetric catalysis, through desymmetrization and kinetic resolution. |
format |
article |
author |
Lei Zhang Shao-Hua Xiang Jun (Joelle) Wang Jian Xiao Jun-Qi Wang Bin Tan |
author_facet |
Lei Zhang Shao-Hua Xiang Jun (Joelle) Wang Jian Xiao Jun-Qi Wang Bin Tan |
author_sort |
Lei Zhang |
title |
Phosphoric acid-catalyzed atroposelective construction of axially chiral arylpyrroles |
title_short |
Phosphoric acid-catalyzed atroposelective construction of axially chiral arylpyrroles |
title_full |
Phosphoric acid-catalyzed atroposelective construction of axially chiral arylpyrroles |
title_fullStr |
Phosphoric acid-catalyzed atroposelective construction of axially chiral arylpyrroles |
title_full_unstemmed |
Phosphoric acid-catalyzed atroposelective construction of axially chiral arylpyrroles |
title_sort |
phosphoric acid-catalyzed atroposelective construction of axially chiral arylpyrroles |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/0d9153db87224e71999d97ccc3260a2f |
work_keys_str_mv |
AT leizhang phosphoricacidcatalyzedatroposelectiveconstructionofaxiallychiralarylpyrroles AT shaohuaxiang phosphoricacidcatalyzedatroposelectiveconstructionofaxiallychiralarylpyrroles AT junjoellewang phosphoricacidcatalyzedatroposelectiveconstructionofaxiallychiralarylpyrroles AT jianxiao phosphoricacidcatalyzedatroposelectiveconstructionofaxiallychiralarylpyrroles AT junqiwang phosphoricacidcatalyzedatroposelectiveconstructionofaxiallychiralarylpyrroles AT bintan phosphoricacidcatalyzedatroposelectiveconstructionofaxiallychiralarylpyrroles |
_version_ |
1718380412185608192 |