The Rational Design of Therapeutic Peptides for Aminopeptidase N using a Substrate-Based Approach
Abstract The M1 family of metalloproteases represents a large number of exopeptidases that cleave single amino acid residues from the N-terminus of peptide substrates. One member of this family that has been well studied is aminopeptidase N (APN), a multifunctional protease known to cleave biologica...
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Auteurs principaux: | , , , , , , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2017
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Accès en ligne: | https://doaj.org/article/0da13595ddc84cff8dba8adb84bdbdf8 |
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