Discovery of fungal oligosaccharide-oxidising flavo-enzymes with previously unknown substrates, redox-activity profiles and interplay with LPMOs

Microbial oxidoreductases are key in biomass breakdown. Here, the authors expand the specificity and redox scope within fungal auxiliary activity 7 family (AA7) enzymes and show that AA7 oligosaccharide dehydrogenases can directly fuel cellulose degradation by lytic polysaccharide monooxygenases.

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Autores principales:	Majid Haddad Momeni, Folmer Fredslund, Bastien Bissaro, Olanrewaju Raji, Thu V. Vuong, Sebastian Meier, Tine Sofie Nielsen, Vincent Lombard, Bruno Guigliarelli, Frédéric Biaso, Mireille Haon, Sacha Grisel, Bernard Henrissat, Ditte Hededam Welner, Emma R. Master, Jean-Guy Berrin, Maher Abou Hachem
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0da8e321f452495c9a48a6a598783fe7
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spelling	oai:doaj.org-article:0da8e321f452495c9a48a6a598783fe72021-12-02T14:37:45ZDiscovery of fungal oligosaccharide-oxidising flavo-enzymes with previously unknown substrates, redox-activity profiles and interplay with LPMOs10.1038/s41467-021-22372-02041-1723https://doaj.org/article/0da8e321f452495c9a48a6a598783fe72021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22372-0https://doaj.org/toc/2041-1723Microbial oxidoreductases are key in biomass breakdown. Here, the authors expand the specificity and redox scope within fungal auxiliary activity 7 family (AA7) enzymes and show that AA7 oligosaccharide dehydrogenases can directly fuel cellulose degradation by lytic polysaccharide monooxygenases.Majid Haddad MomeniFolmer FredslundBastien BissaroOlanrewaju RajiThu V. VuongSebastian MeierTine Sofie NielsenVincent LombardBruno GuigliarelliFrédéric BiasoMireille HaonSacha GriselBernard HenrissatDitte Hededam WelnerEmma R. MasterJean-Guy BerrinMaher Abou HachemNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Majid Haddad Momeni Folmer Fredslund Bastien Bissaro Olanrewaju Raji Thu V. Vuong Sebastian Meier Tine Sofie Nielsen Vincent Lombard Bruno Guigliarelli Frédéric Biaso Mireille Haon Sacha Grisel Bernard Henrissat Ditte Hededam Welner Emma R. Master Jean-Guy Berrin Maher Abou Hachem Discovery of fungal oligosaccharide-oxidising flavo-enzymes with previously unknown substrates, redox-activity profiles and interplay with LPMOs
description	Microbial oxidoreductases are key in biomass breakdown. Here, the authors expand the specificity and redox scope within fungal auxiliary activity 7 family (AA7) enzymes and show that AA7 oligosaccharide dehydrogenases can directly fuel cellulose degradation by lytic polysaccharide monooxygenases.
format	article
author	Majid Haddad Momeni Folmer Fredslund Bastien Bissaro Olanrewaju Raji Thu V. Vuong Sebastian Meier Tine Sofie Nielsen Vincent Lombard Bruno Guigliarelli Frédéric Biaso Mireille Haon Sacha Grisel Bernard Henrissat Ditte Hededam Welner Emma R. Master Jean-Guy Berrin Maher Abou Hachem
author_facet	Majid Haddad Momeni Folmer Fredslund Bastien Bissaro Olanrewaju Raji Thu V. Vuong Sebastian Meier Tine Sofie Nielsen Vincent Lombard Bruno Guigliarelli Frédéric Biaso Mireille Haon Sacha Grisel Bernard Henrissat Ditte Hededam Welner Emma R. Master Jean-Guy Berrin Maher Abou Hachem
author_sort	Majid Haddad Momeni
title	Discovery of fungal oligosaccharide-oxidising flavo-enzymes with previously unknown substrates, redox-activity profiles and interplay with LPMOs
title_short	Discovery of fungal oligosaccharide-oxidising flavo-enzymes with previously unknown substrates, redox-activity profiles and interplay with LPMOs
title_full	Discovery of fungal oligosaccharide-oxidising flavo-enzymes with previously unknown substrates, redox-activity profiles and interplay with LPMOs
title_fullStr	Discovery of fungal oligosaccharide-oxidising flavo-enzymes with previously unknown substrates, redox-activity profiles and interplay with LPMOs
title_full_unstemmed	Discovery of fungal oligosaccharide-oxidising flavo-enzymes with previously unknown substrates, redox-activity profiles and interplay with LPMOs
title_sort	discovery of fungal oligosaccharide-oxidising flavo-enzymes with previously unknown substrates, redox-activity profiles and interplay with lpmos
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0da8e321f452495c9a48a6a598783fe7
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Discovery of fungal oligosaccharide-oxidising flavo-enzymes with previously unknown substrates, redox-activity profiles and interplay with LPMOs

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