Broadly neutralizing plasma antibodies effective against autologous circulating viruses in infants with multivariant HIV-1 infection

Some infants develop broadly neutralizing antibodies (bnAbs) to HIV in a shorter time frame than adults, but the reasons aren’t well understood. Here, the authors study a cohort of 51 HIV-1 clade C perinatally infected infants of Indian origin and find that multivariant infection is associated with...

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Autores principales:	Nitesh Mishra, Shaifali Sharma, Ayushman Dobhal, Sanjeev Kumar, Himanshi Chawla, Ravinder Singh, Muzamil Ashraf Makhdoomi, Bimal Kumar Das, Rakesh Lodha, Sushil Kumar Kabra, Kalpana Luthra
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0dc11c97dcc845ddb653c4c07121885e
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spelling	oai:doaj.org-article:0dc11c97dcc845ddb653c4c07121885e2021-12-02T16:38:50ZBroadly neutralizing plasma antibodies effective against autologous circulating viruses in infants with multivariant HIV-1 infection10.1038/s41467-020-18225-x2041-1723https://doaj.org/article/0dc11c97dcc845ddb653c4c07121885e2020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18225-xhttps://doaj.org/toc/2041-1723Some infants develop broadly neutralizing antibodies (bnAbs) to HIV in a shorter time frame than adults, but the reasons aren’t well understood. Here, the authors study a cohort of 51 HIV-1 clade C perinatally infected infants of Indian origin and find that multivariant infection is associated with bnAbs in elite neutralizers.Nitesh MishraShaifali SharmaAyushman DobhalSanjeev KumarHimanshi ChawlaRavinder SinghMuzamil Ashraf MakhdoomiBimal Kumar DasRakesh LodhaSushil Kumar KabraKalpana LuthraNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nitesh Mishra Shaifali Sharma Ayushman Dobhal Sanjeev Kumar Himanshi Chawla Ravinder Singh Muzamil Ashraf Makhdoomi Bimal Kumar Das Rakesh Lodha Sushil Kumar Kabra Kalpana Luthra Broadly neutralizing plasma antibodies effective against autologous circulating viruses in infants with multivariant HIV-1 infection
description	Some infants develop broadly neutralizing antibodies (bnAbs) to HIV in a shorter time frame than adults, but the reasons aren’t well understood. Here, the authors study a cohort of 51 HIV-1 clade C perinatally infected infants of Indian origin and find that multivariant infection is associated with bnAbs in elite neutralizers.
format	article
author	Nitesh Mishra Shaifali Sharma Ayushman Dobhal Sanjeev Kumar Himanshi Chawla Ravinder Singh Muzamil Ashraf Makhdoomi Bimal Kumar Das Rakesh Lodha Sushil Kumar Kabra Kalpana Luthra
author_facet	Nitesh Mishra Shaifali Sharma Ayushman Dobhal Sanjeev Kumar Himanshi Chawla Ravinder Singh Muzamil Ashraf Makhdoomi Bimal Kumar Das Rakesh Lodha Sushil Kumar Kabra Kalpana Luthra
author_sort	Nitesh Mishra
title	Broadly neutralizing plasma antibodies effective against autologous circulating viruses in infants with multivariant HIV-1 infection
title_short	Broadly neutralizing plasma antibodies effective against autologous circulating viruses in infants with multivariant HIV-1 infection
title_full	Broadly neutralizing plasma antibodies effective against autologous circulating viruses in infants with multivariant HIV-1 infection
title_fullStr	Broadly neutralizing plasma antibodies effective against autologous circulating viruses in infants with multivariant HIV-1 infection
title_full_unstemmed	Broadly neutralizing plasma antibodies effective against autologous circulating viruses in infants with multivariant HIV-1 infection
title_sort	broadly neutralizing plasma antibodies effective against autologous circulating viruses in infants with multivariant hiv-1 infection
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/0dc11c97dcc845ddb653c4c07121885e
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Broadly neutralizing plasma antibodies effective against autologous circulating viruses in infants with multivariant HIV-1 infection

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