Lipoprotein <italic toggle="yes">N</italic>-Acylation in <italic toggle="yes">Staphylococcus aureus</italic> Is Catalyzed by a Two-Component Acyl Transferase System

Lipoprotein <italic toggle="yes">N</italic>-Acylation in <italic toggle="yes">Staphylococcus aureus</italic> Is Catalyzed by a Two-Component Acyl Transferase System

ABSTRACT Bacterial lipoproteins (Lpps) are a class of membrane-associated proteins universally distributed among all bacteria. A characteristic N-terminal cysteine residue that is variably acylated anchors C-terminal globular domains to the extracellular surface, where they serve numerous roles, inc...

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Autores principales: John H. Gardiner, Gloria Komazin, Miki Matsuo, Kaitlin Cole, Friedrich Götz, Timothy C. Meredith
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
Staphylococcus
Staphylococcus aureus
TLR2
acyl transferases
immune response
lipoproteins
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/0dc2e21b11354398ab1fff8f78158146
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