Carbon nano-onion-mediated dual targeting of P-selectin and P-glycoprotein to overcome cancer drug resistance
The transmembrane P-glycoprotein (P-gp) pumps are known to promote drug resistance by enhancing drug efflux. Here, the authors deliver P-gp inhibitor and a chemotherapeutic agent using tumor blood vessel-targeting nanoparticle, to overcome drug resistance.
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| Autores principales: | , , , , , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/0dcc96fe3e8f47d092bab3e71efd82f3 |
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| Sumario: | The transmembrane P-glycoprotein (P-gp) pumps are known to promote drug resistance by enhancing drug efflux. Here, the authors deliver P-gp inhibitor and a chemotherapeutic agent using tumor blood vessel-targeting nanoparticle, to overcome drug resistance. |
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