Promysalin is a salicylate-containing antimicrobial with a cell-membrane-disrupting mechanism of action on Gram-positive bacteria

Promysalin is a salicylate-containing antimicrobial with a cell-membrane-disrupting mechanism of action on Gram-positive bacteria

Abstract Promysalin was previously described as a narrow spectrum molecule with a unique species-specific activity against Pseudomonas aeruginosa. Here we demonstrate that promysalin is active against Gram-positive and Gram-negative bacteria using a microdilution assay. Promysalin acts on Gram-posit...

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Autores principales: Rahul D. Kaduskar, Giulia Della Scala, Zaaima J. H. Al Jabri, Stefania Arioli, Loana Musso, Marco R. Oggioni, Sabrina Dallavalle, Diego Mora
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/0dd31ffb6b3f4aeeb329171fd250c465
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