Antibiotic prophylaxis: different practice patterns within and outside the United States

Stephen G Schwartz,1 Andrzej Grzybowski,2 Harry W Flynn Jr1 1Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA; 2Department of Ophthalmology, Poznan City Hospital, Poznan, Poland Abstract: Endophthalmitis remains a rare but impo...

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Autores principales: Schwartz SG, Grzybowski A, Flynn HW Jr
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Lenguaje:EN
Publicado: Dove Medical Press 2016
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Acceso en línea:https://doaj.org/article/0dd8f623bbbf4322b00f6aad4b80e4be
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spelling oai:doaj.org-article:0dd8f623bbbf4322b00f6aad4b80e4be2021-12-02T07:20:10ZAntibiotic prophylaxis: different practice patterns within and outside the United States1177-5483https://doaj.org/article/0dd8f623bbbf4322b00f6aad4b80e4be2016-01-01T00:00:00Zhttps://www.dovepress.com/antibiotic-prophylaxis-different-practice-patterns-within-and-outside--peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Stephen G Schwartz,1 Andrzej Grzybowski,2 Harry W Flynn Jr1 1Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA; 2Department of Ophthalmology, Poznan City Hospital, Poznan, Poland Abstract: Endophthalmitis remains a rare but important cause of visual loss. Prophylaxis strategies are important to reduce rates of endophthalmitis after cataract surgery, intravitreal injection, and other procedures. There is substantial variability between the US and the rest of the world. During cataract surgery, intracameral antibiotics are commonly used in many nations, especially in Europe, but are less commonly used in the US. A randomized clinical trial from the European Society of Cataract and Refractive Surgeons reported an approximately fivefold reduction in endophthalmitis rates associated with intracameral cefuroxime but these results are controversial. There are no randomized clinical trials regarding endophthalmitis associated with intravitreal injection. Topical antibiotics are commonly used in many nations, but are less commonly used in the US. At this time, there is no global consensus and it appears unlikely that additional major clinical trials will conclusively define the optimal endophthalmitis prophylaxis techniques. Keywords: cataract surgery, endophthalmitis, intracameral antibiotic, intravitreal injection, prophylaxisSchwartz SGGrzybowski AFlynn HW JrDove Medical PressarticleCataract surgeryEndophthalmitisIntracameral antibioticIntravitreal injectionProphylaxisOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2016, Iss Issue 1, Pp 251-256 (2016)
institution DOAJ
collection DOAJ
language EN
topic Cataract surgery
Endophthalmitis
Intracameral antibiotic
Intravitreal injection
Prophylaxis
Ophthalmology
RE1-994
spellingShingle Cataract surgery
Endophthalmitis
Intracameral antibiotic
Intravitreal injection
Prophylaxis
Ophthalmology
RE1-994
Schwartz SG
Grzybowski A
Flynn HW Jr
Antibiotic prophylaxis: different practice patterns within and outside the United States
description Stephen G Schwartz,1 Andrzej Grzybowski,2 Harry W Flynn Jr1 1Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA; 2Department of Ophthalmology, Poznan City Hospital, Poznan, Poland Abstract: Endophthalmitis remains a rare but important cause of visual loss. Prophylaxis strategies are important to reduce rates of endophthalmitis after cataract surgery, intravitreal injection, and other procedures. There is substantial variability between the US and the rest of the world. During cataract surgery, intracameral antibiotics are commonly used in many nations, especially in Europe, but are less commonly used in the US. A randomized clinical trial from the European Society of Cataract and Refractive Surgeons reported an approximately fivefold reduction in endophthalmitis rates associated with intracameral cefuroxime but these results are controversial. There are no randomized clinical trials regarding endophthalmitis associated with intravitreal injection. Topical antibiotics are commonly used in many nations, but are less commonly used in the US. At this time, there is no global consensus and it appears unlikely that additional major clinical trials will conclusively define the optimal endophthalmitis prophylaxis techniques. Keywords: cataract surgery, endophthalmitis, intracameral antibiotic, intravitreal injection, prophylaxis
format article
author Schwartz SG
Grzybowski A
Flynn HW Jr
author_facet Schwartz SG
Grzybowski A
Flynn HW Jr
author_sort Schwartz SG
title Antibiotic prophylaxis: different practice patterns within and outside the United States
title_short Antibiotic prophylaxis: different practice patterns within and outside the United States
title_full Antibiotic prophylaxis: different practice patterns within and outside the United States
title_fullStr Antibiotic prophylaxis: different practice patterns within and outside the United States
title_full_unstemmed Antibiotic prophylaxis: different practice patterns within and outside the United States
title_sort antibiotic prophylaxis: different practice patterns within and outside the united states
publisher Dove Medical Press
publishDate 2016
url https://doaj.org/article/0dd8f623bbbf4322b00f6aad4b80e4be
work_keys_str_mv AT schwartzsg antibioticprophylaxisdifferentpracticepatternswithinandoutsidetheunitedstates
AT grzybowskia antibioticprophylaxisdifferentpracticepatternswithinandoutsidetheunitedstates
AT flynnhwjr antibioticprophylaxisdifferentpracticepatternswithinandoutsidetheunitedstates
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