Association of maternal history of neonatal death with subsequent neonatal death across 56 low- and middle-income countries

Abstract Early identification of high-risk pregnancies can reduce global neonatal mortality rate. Using the most recent Demographic and Health Surveys from 56 low- and middle-income countries, we examined the proportion of mothers with history of neonatal deaths. Logistic regression models were used...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Zhihui Li, Mudit Kapoor, Rockli Kim, S. V. Subramanian
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/0dde83a5cecc465487691e220e124ed0
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:0dde83a5cecc465487691e220e124ed0
record_format	dspace
spelling	oai:doaj.org-article:0dde83a5cecc465487691e220e124ed02021-12-02T18:01:48ZAssociation of maternal history of neonatal death with subsequent neonatal death across 56 low- and middle-income countries10.1038/s41598-021-97481-32045-2322https://doaj.org/article/0dde83a5cecc465487691e220e124ed02021-10-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-97481-3https://doaj.org/toc/2045-2322Abstract Early identification of high-risk pregnancies can reduce global neonatal mortality rate. Using the most recent Demographic and Health Surveys from 56 low- and middle-income countries, we examined the proportion of mothers with history of neonatal deaths. Logistic regression models were used to assess the association between maternal history of neonatal death and subsequent neonatal mortality. The adjusted models controlled for socioeconomic, child, and pregnancy-related factors. Country-specific analyses were performed to assess heterogeneity in this association across countries. Among the 437,049 live births included in the study, 6910 resulted in neonatal deaths. In general, 22.4% (1549) occurred to mothers with previous history of neonatal death; at the country-level, this proportion ranged from 1.2% (95% confidence interval [CI] 0.0, 2.6) in Dominican Republic to 38.1% (95% CI 26.0, 50.1) in Niger. Maternal history of neonatal death was significantly associated with subsequent neonatal death in both the pooled and the subgroup analyses. In the fully adjusted model, history of neonatal death was associated with 2.1 (95% CI 1.9, 2.4) times higher odds of subsequent neonatal mortality in the pooled analysis. We observed large variation in the associations across countries ranging from fully adjusted odds ratio (FAOR) of 0.4 (95% CI 0.0, 4.0) in Dominican Republic to 16.1 (95% CI 3.6, 42.0) in South Africa. Our study suggests that maternal history of neonatal death could be an effective early identifier of high-risk pregnancies in resource-poor countries. However, country-specific contexts must be considered in national policy discussions.Zhihui LiMudit KapoorRockli KimS. V. SubramanianNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Zhihui Li Mudit Kapoor Rockli Kim S. V. Subramanian Association of maternal history of neonatal death with subsequent neonatal death across 56 low- and middle-income countries
description	Abstract Early identification of high-risk pregnancies can reduce global neonatal mortality rate. Using the most recent Demographic and Health Surveys from 56 low- and middle-income countries, we examined the proportion of mothers with history of neonatal deaths. Logistic regression models were used to assess the association between maternal history of neonatal death and subsequent neonatal mortality. The adjusted models controlled for socioeconomic, child, and pregnancy-related factors. Country-specific analyses were performed to assess heterogeneity in this association across countries. Among the 437,049 live births included in the study, 6910 resulted in neonatal deaths. In general, 22.4% (1549) occurred to mothers with previous history of neonatal death; at the country-level, this proportion ranged from 1.2% (95% confidence interval [CI] 0.0, 2.6) in Dominican Republic to 38.1% (95% CI 26.0, 50.1) in Niger. Maternal history of neonatal death was significantly associated with subsequent neonatal death in both the pooled and the subgroup analyses. In the fully adjusted model, history of neonatal death was associated with 2.1 (95% CI 1.9, 2.4) times higher odds of subsequent neonatal mortality in the pooled analysis. We observed large variation in the associations across countries ranging from fully adjusted odds ratio (FAOR) of 0.4 (95% CI 0.0, 4.0) in Dominican Republic to 16.1 (95% CI 3.6, 42.0) in South Africa. Our study suggests that maternal history of neonatal death could be an effective early identifier of high-risk pregnancies in resource-poor countries. However, country-specific contexts must be considered in national policy discussions.
format	article
author	Zhihui Li Mudit Kapoor Rockli Kim S. V. Subramanian
author_facet	Zhihui Li Mudit Kapoor Rockli Kim S. V. Subramanian
author_sort	Zhihui Li
title	Association of maternal history of neonatal death with subsequent neonatal death across 56 low- and middle-income countries
title_short	Association of maternal history of neonatal death with subsequent neonatal death across 56 low- and middle-income countries
title_full	Association of maternal history of neonatal death with subsequent neonatal death across 56 low- and middle-income countries
title_fullStr	Association of maternal history of neonatal death with subsequent neonatal death across 56 low- and middle-income countries
title_full_unstemmed	Association of maternal history of neonatal death with subsequent neonatal death across 56 low- and middle-income countries
title_sort	association of maternal history of neonatal death with subsequent neonatal death across 56 low- and middle-income countries
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0dde83a5cecc465487691e220e124ed0
work_keys_str_mv	AT zhihuili associationofmaternalhistoryofneonataldeathwithsubsequentneonataldeathacross56lowandmiddleincomecountries AT muditkapoor associationofmaternalhistoryofneonataldeathwithsubsequentneonataldeathacross56lowandmiddleincomecountries AT rocklikim associationofmaternalhistoryofneonataldeathwithsubsequentneonataldeathacross56lowandmiddleincomecountries AT svsubramanian associationofmaternalhistoryofneonataldeathwithsubsequentneonataldeathacross56lowandmiddleincomecountries
_version_	1718378910429741056

Association of maternal history of neonatal death with subsequent neonatal death across 56 low- and middle-income countries

Ejemplares similares