A Two-Step Mechanism for the Activation of Actinorhodin Export and Resistance in <named-content content-type="genus-species">Streptomyces coelicolor</named-content>
ABSTRACT Many microorganisms produce secondary metabolites that have antibiotic activity. To avoid self-inhibition, the producing cells often encode cognate export and/or resistance mechanisms in the biosynthetic gene clusters for these molecules. Actinorhodin is a blue-pigmented antibiotic produced...
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Autores principales: | Ye Xu, Andrew Willems, Catherine Au-yeung, Kapil Tahlan, Justin R. Nodwell |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/0de435cca3ca4bc693ec2a1ff6b2842b |
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