The Arabidopsis NOT4A E3 ligase promotes PGR3 expression and regulates chloroplast translation

NOT4 proteins associate with ribosomes and are required for co-translational quality control in yeast and animals. Here, Bailey et al. show that Arabidopsis NOT4A positively regulates the expression of the nuclear encoded pentatricopeptide repeat (PPR) protein PGR3 and is required for ribosome bioge...

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Autores principales: Mark Bailey, Aiste Ivanauskaite, Julia Grimmer, Oluwatunmise Akintewe, Adrienne C. Payne, Rory Osborne, Anne-Marie Labandera, Ross D. Etherington, Marjaana Rantala, Sacha Baginsky, Paula Mulo, Daniel J. Gibbs
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/0dfb3d3254a24f27aa5722f850a7ce71
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Sumario:NOT4 proteins associate with ribosomes and are required for co-translational quality control in yeast and animals. Here, Bailey et al. show that Arabidopsis NOT4A positively regulates the expression of the nuclear encoded pentatricopeptide repeat (PPR) protein PGR3 and is required for ribosome biogenesis and mRNA translation in the chloroplast.