Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids

Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids

Coptis chinensis represents an early-diverging eudicot lineage with diverse medicinal applications. Here, the authors report its chromosome-scale genome assembly, infer a single ancient whole-genome duplication, and characterize the function of CYP719 in diversification of protoberberine-type alkalo...

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Autores principales: Yifei Liu, Bo Wang, Shaohua Shu, Zheng Li, Chi Song, Di Liu, Yan Niu, Jinxin Liu, Jingjing Zhang, Heping Liu, Zhigang Hu, Bisheng Huang, Xiuyu Liu, Wei Liu, Liping Jiang, Mohammad Murtaza Alami, Yuxin Zhou, Yutao Ma, Xiangxiang He, Yicheng Yang, Tianyuan Zhang, Hui Hu, Michael S. Barker, Shilin Chen, Xuekui Wang, Jing Nie
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/0dfcbbd6d5624e58bec78bf6f91cb8b9
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spelling oai:doaj.org-article:0dfcbbd6d5624e58bec78bf6f91cb8b92021-12-02T17:51:19ZAnalysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids10.1038/s41467-021-23611-02041-1723https://doaj.org/article/0dfcbbd6d5624e58bec78bf6f91cb8b92021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23611-0https://doaj.org/toc/2041-1723Coptis chinensis represents an early-diverging eudicot lineage with diverse medicinal applications. Here, the authors report its chromosome-scale genome assembly, infer a single ancient whole-genome duplication, and characterize the function of CYP719 in diversification of protoberberine-type alkaloids.Yifei LiuBo WangShaohua ShuZheng LiChi SongDi LiuYan NiuJinxin LiuJingjing ZhangHeping LiuZhigang HuBisheng HuangXiuyu LiuWei LiuLiping JiangMohammad Murtaza AlamiYuxin ZhouYutao MaXiangxiang HeYicheng YangTianyuan ZhangHui HuMichael S. BarkerShilin ChenXuekui WangJing NieNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yifei Liu
Bo Wang
Shaohua Shu
Zheng Li
Chi Song
Di Liu
Yan Niu
Jinxin Liu
Jingjing Zhang
Heping Liu
Zhigang Hu
Bisheng Huang
Xiuyu Liu
Wei Liu
Liping Jiang
Mohammad Murtaza Alami
Yuxin Zhou
Yutao Ma
Xiangxiang He
Yicheng Yang
Tianyuan Zhang
Hui Hu
Michael S. Barker
Shilin Chen
Xuekui Wang
Jing Nie
Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids
description Coptis chinensis represents an early-diverging eudicot lineage with diverse medicinal applications. Here, the authors report its chromosome-scale genome assembly, infer a single ancient whole-genome duplication, and characterize the function of CYP719 in diversification of protoberberine-type alkaloids.
format article
author Yifei Liu
Bo Wang
Shaohua Shu
Zheng Li
Chi Song
Di Liu
Yan Niu
Jinxin Liu
Jingjing Zhang
Heping Liu
Zhigang Hu
Bisheng Huang
Xiuyu Liu
Wei Liu
Liping Jiang
Mohammad Murtaza Alami
Yuxin Zhou
Yutao Ma
Xiangxiang He
Yicheng Yang
Tianyuan Zhang
Hui Hu
Michael S. Barker
Shilin Chen
Xuekui Wang
Jing Nie
author_facet Yifei Liu
Bo Wang
Shaohua Shu
Zheng Li
Chi Song
Di Liu
Yan Niu
Jinxin Liu
Jingjing Zhang
Heping Liu
Zhigang Hu
Bisheng Huang
Xiuyu Liu
Wei Liu
Liping Jiang
Mohammad Murtaza Alami
Yuxin Zhou
Yutao Ma
Xiangxiang He
Yicheng Yang
Tianyuan Zhang
Hui Hu
Michael S. Barker
Shilin Chen
Xuekui Wang
Jing Nie
author_sort Yifei Liu
title Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids
title_short Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids
title_full Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids
title_fullStr Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids
title_full_unstemmed Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids
title_sort analysis of the coptis chinensis genome reveals the diversification of protoberberine-type alkaloids
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/0dfcbbd6d5624e58bec78bf6f91cb8b9
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