Epigenetic dysregulation of naive CD4+ T-cell activation genes in childhood food allergy

Immunoglobulin E (IgE)-mediated food allergy is a major issue that affects 2–10% of infants. Here the authors study the epigenetic regulation of the naive CD4+ T cell activation response among children with IgE-mediated food allergy finding epigenetic dysregulation in the early stages of signal tran...

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Autores principales:	David Martino, Melanie Neeland, Thanh Dang, Joanna Cobb, Justine Ellis, Alice Barnett, Mimi Tang, Peter Vuillermin, Katrina Allen, Richard Saffery
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0e00e3ea4f0f49e7aa6f75a5b732081b
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spelling	oai:doaj.org-article:0e00e3ea4f0f49e7aa6f75a5b732081b2021-12-02T14:40:06ZEpigenetic dysregulation of naive CD4+ T-cell activation genes in childhood food allergy10.1038/s41467-018-05608-42041-1723https://doaj.org/article/0e00e3ea4f0f49e7aa6f75a5b732081b2018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05608-4https://doaj.org/toc/2041-1723Immunoglobulin E (IgE)-mediated food allergy is a major issue that affects 2–10% of infants. Here the authors study the epigenetic regulation of the naive CD4+ T cell activation response among children with IgE-mediated food allergy finding epigenetic dysregulation in the early stages of signal transduction through the T cell receptor complex.David MartinoMelanie NeelandThanh DangJoanna CobbJustine EllisAlice BarnettMimi TangPeter VuillerminKatrina AllenRichard SafferyNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q David Martino Melanie Neeland Thanh Dang Joanna Cobb Justine Ellis Alice Barnett Mimi Tang Peter Vuillermin Katrina Allen Richard Saffery Epigenetic dysregulation of naive CD4+ T-cell activation genes in childhood food allergy
description	Immunoglobulin E (IgE)-mediated food allergy is a major issue that affects 2–10% of infants. Here the authors study the epigenetic regulation of the naive CD4+ T cell activation response among children with IgE-mediated food allergy finding epigenetic dysregulation in the early stages of signal transduction through the T cell receptor complex.
format	article
author	David Martino Melanie Neeland Thanh Dang Joanna Cobb Justine Ellis Alice Barnett Mimi Tang Peter Vuillermin Katrina Allen Richard Saffery
author_facet	David Martino Melanie Neeland Thanh Dang Joanna Cobb Justine Ellis Alice Barnett Mimi Tang Peter Vuillermin Katrina Allen Richard Saffery
author_sort	David Martino
title	Epigenetic dysregulation of naive CD4+ T-cell activation genes in childhood food allergy
title_short	Epigenetic dysregulation of naive CD4+ T-cell activation genes in childhood food allergy
title_full	Epigenetic dysregulation of naive CD4+ T-cell activation genes in childhood food allergy
title_fullStr	Epigenetic dysregulation of naive CD4+ T-cell activation genes in childhood food allergy
title_full_unstemmed	Epigenetic dysregulation of naive CD4+ T-cell activation genes in childhood food allergy
title_sort	epigenetic dysregulation of naive cd4+ t-cell activation genes in childhood food allergy
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/0e00e3ea4f0f49e7aa6f75a5b732081b
work_keys_str_mv	AT davidmartino epigeneticdysregulationofnaivecd4tcellactivationgenesinchildhoodfoodallergy AT melanieneeland epigeneticdysregulationofnaivecd4tcellactivationgenesinchildhoodfoodallergy AT thanhdang epigeneticdysregulationofnaivecd4tcellactivationgenesinchildhoodfoodallergy AT joannacobb epigeneticdysregulationofnaivecd4tcellactivationgenesinchildhoodfoodallergy AT justineellis epigeneticdysregulationofnaivecd4tcellactivationgenesinchildhoodfoodallergy AT alicebarnett epigeneticdysregulationofnaivecd4tcellactivationgenesinchildhoodfoodallergy AT mimitang epigeneticdysregulationofnaivecd4tcellactivationgenesinchildhoodfoodallergy AT petervuillermin epigeneticdysregulationofnaivecd4tcellactivationgenesinchildhoodfoodallergy AT katrinaallen epigeneticdysregulationofnaivecd4tcellactivationgenesinchildhoodfoodallergy AT richardsaffery epigeneticdysregulationofnaivecd4tcellactivationgenesinchildhoodfoodallergy
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Epigenetic dysregulation of naive CD4+ T-cell activation genes in childhood food allergy

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