Postpartum breast cancer has a distinct molecular profile that predicts poor outcomes

The molecular differences between postpartum (PPBC) and nulliparous (NPBC) young women breast cancer (YWBC) patients remain unknown. Here the authors perform RNA sequencing and multiplex immunohistochemistry on an FFPE breast cancer cohort and suggest that PPBC is a unique entity within YWBC with po...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Sonali Jindal, Nathan D. Pennock, Duanchen Sun, Wesley Horton, Michelle K. Ozaki, Jayasri Narasimhan, Alexandra Q. Bartlett, Sheila Weinmann, Paul E. Goss, Virginia F. Borges, Zheng Xia, Pepper Schedin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Q
Acceso en línea:https://doaj.org/article/0e10b40c44fd4f99a9a9f2ec3a3bf0dd
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:0e10b40c44fd4f99a9a9f2ec3a3bf0dd
record_format dspace
spelling oai:doaj.org-article:0e10b40c44fd4f99a9a9f2ec3a3bf0dd2021-11-08T11:05:32ZPostpartum breast cancer has a distinct molecular profile that predicts poor outcomes10.1038/s41467-021-26505-32041-1723https://doaj.org/article/0e10b40c44fd4f99a9a9f2ec3a3bf0dd2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26505-3https://doaj.org/toc/2041-1723The molecular differences between postpartum (PPBC) and nulliparous (NPBC) young women breast cancer (YWBC) patients remain unknown. Here the authors perform RNA sequencing and multiplex immunohistochemistry on an FFPE breast cancer cohort and suggest that PPBC is a unique entity within YWBC with poor prognosis.Sonali JindalNathan D. PennockDuanchen SunWesley HortonMichelle K. OzakiJayasri NarasimhanAlexandra Q. BartlettSheila WeinmannPaul E. GossVirginia F. BorgesZheng XiaPepper SchedinNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sonali Jindal
Nathan D. Pennock
Duanchen Sun
Wesley Horton
Michelle K. Ozaki
Jayasri Narasimhan
Alexandra Q. Bartlett
Sheila Weinmann
Paul E. Goss
Virginia F. Borges
Zheng Xia
Pepper Schedin
Postpartum breast cancer has a distinct molecular profile that predicts poor outcomes
description The molecular differences between postpartum (PPBC) and nulliparous (NPBC) young women breast cancer (YWBC) patients remain unknown. Here the authors perform RNA sequencing and multiplex immunohistochemistry on an FFPE breast cancer cohort and suggest that PPBC is a unique entity within YWBC with poor prognosis.
format article
author Sonali Jindal
Nathan D. Pennock
Duanchen Sun
Wesley Horton
Michelle K. Ozaki
Jayasri Narasimhan
Alexandra Q. Bartlett
Sheila Weinmann
Paul E. Goss
Virginia F. Borges
Zheng Xia
Pepper Schedin
author_facet Sonali Jindal
Nathan D. Pennock
Duanchen Sun
Wesley Horton
Michelle K. Ozaki
Jayasri Narasimhan
Alexandra Q. Bartlett
Sheila Weinmann
Paul E. Goss
Virginia F. Borges
Zheng Xia
Pepper Schedin
author_sort Sonali Jindal
title Postpartum breast cancer has a distinct molecular profile that predicts poor outcomes
title_short Postpartum breast cancer has a distinct molecular profile that predicts poor outcomes
title_full Postpartum breast cancer has a distinct molecular profile that predicts poor outcomes
title_fullStr Postpartum breast cancer has a distinct molecular profile that predicts poor outcomes
title_full_unstemmed Postpartum breast cancer has a distinct molecular profile that predicts poor outcomes
title_sort postpartum breast cancer has a distinct molecular profile that predicts poor outcomes
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/0e10b40c44fd4f99a9a9f2ec3a3bf0dd
work_keys_str_mv AT sonalijindal postpartumbreastcancerhasadistinctmolecularprofilethatpredictspooroutcomes
AT nathandpennock postpartumbreastcancerhasadistinctmolecularprofilethatpredictspooroutcomes
AT duanchensun postpartumbreastcancerhasadistinctmolecularprofilethatpredictspooroutcomes
AT wesleyhorton postpartumbreastcancerhasadistinctmolecularprofilethatpredictspooroutcomes
AT michellekozaki postpartumbreastcancerhasadistinctmolecularprofilethatpredictspooroutcomes
AT jayasrinarasimhan postpartumbreastcancerhasadistinctmolecularprofilethatpredictspooroutcomes
AT alexandraqbartlett postpartumbreastcancerhasadistinctmolecularprofilethatpredictspooroutcomes
AT sheilaweinmann postpartumbreastcancerhasadistinctmolecularprofilethatpredictspooroutcomes
AT paulegoss postpartumbreastcancerhasadistinctmolecularprofilethatpredictspooroutcomes
AT virginiafborges postpartumbreastcancerhasadistinctmolecularprofilethatpredictspooroutcomes
AT zhengxia postpartumbreastcancerhasadistinctmolecularprofilethatpredictspooroutcomes
AT pepperschedin postpartumbreastcancerhasadistinctmolecularprofilethatpredictspooroutcomes
_version_ 1718442306437120000