Inotropes in Acute Heart Failure: From Guidelines to Practical Use: Therapeutic Options and Clinical Practice

Inotropes are pharmacological agents that are indicated for the treatment of patients presenting with acute heart failure (AHF) with concomitant hypoperfusion due to decreased cardiac output. They are usually administered for a short period during the initial management of AHF until haemodynamic sta...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Vasiliki Bistola, Angelos Arfaras-Melainis, Eftihia Polyzogopoulou, Ignatios Ikonomidis, John Parissis
Formato:	article
Lenguaje:	EN
Publicado:	Radcliffe Medical Media 2019
Materias:	Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/0e11d0ccd47948c2b9b2449bc12d3d81
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:0e11d0ccd47948c2b9b2449bc12d3d81
record_format	dspace
spelling	oai:doaj.org-article:0e11d0ccd47948c2b9b2449bc12d3d812021-12-04T16:01:59ZInotropes in Acute Heart Failure: From Guidelines to Practical Use: Therapeutic Options and Clinical Practice10.15420/cfr.2019.11.22057-75592057-7540https://doaj.org/article/0e11d0ccd47948c2b9b2449bc12d3d812019-11-01T00:00:00Zhttps://www.cfrjournal.com/articles/Inotropes-in-Acute-Heart-Failurehttps://doaj.org/toc/2057-7540https://doaj.org/toc/2057-7559Inotropes are pharmacological agents that are indicated for the treatment of patients presenting with acute heart failure (AHF) with concomitant hypoperfusion due to decreased cardiac output. They are usually administered for a short period during the initial management of AHF until haemodynamic stabilisation and restoration of peripheral perfusion occur. They can be used for longer periods to support patients as a bridge to a more definite treatment, such as transplant of left ventricular assist devices, or as part of a palliative care regimen. The currently available inotropic agents in clinical practice fall into three main categories: beta-agonists, phosphodiesterase III inhibitors and calcium sensitisers. However, due to the well-documented potential for adverse events and their association with increased long-term mortality, physicians should be aware of the indications and dosing strategies suitable for different types of patients. Novel inotropes that use alternative intracellular pathways are under investigation, in an effort to minimise the drawbacks that conventional inotropes exhibit.Vasiliki BistolaAngelos Arfaras-MelainisEftihia PolyzogopoulouIgnatios IkonomidisJohn ParissisRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENCardiac Failure Review , Vol 5, Iss 3, Pp 133-139 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	Diseases of the circulatory (Cardiovascular) system RC666-701 Vasiliki Bistola Angelos Arfaras-Melainis Eftihia Polyzogopoulou Ignatios Ikonomidis John Parissis Inotropes in Acute Heart Failure: From Guidelines to Practical Use: Therapeutic Options and Clinical Practice
description	Inotropes are pharmacological agents that are indicated for the treatment of patients presenting with acute heart failure (AHF) with concomitant hypoperfusion due to decreased cardiac output. They are usually administered for a short period during the initial management of AHF until haemodynamic stabilisation and restoration of peripheral perfusion occur. They can be used for longer periods to support patients as a bridge to a more definite treatment, such as transplant of left ventricular assist devices, or as part of a palliative care regimen. The currently available inotropic agents in clinical practice fall into three main categories: beta-agonists, phosphodiesterase III inhibitors and calcium sensitisers. However, due to the well-documented potential for adverse events and their association with increased long-term mortality, physicians should be aware of the indications and dosing strategies suitable for different types of patients. Novel inotropes that use alternative intracellular pathways are under investigation, in an effort to minimise the drawbacks that conventional inotropes exhibit.
format	article
author	Vasiliki Bistola Angelos Arfaras-Melainis Eftihia Polyzogopoulou Ignatios Ikonomidis John Parissis
author_facet	Vasiliki Bistola Angelos Arfaras-Melainis Eftihia Polyzogopoulou Ignatios Ikonomidis John Parissis
author_sort	Vasiliki Bistola
title	Inotropes in Acute Heart Failure: From Guidelines to Practical Use: Therapeutic Options and Clinical Practice
title_short	Inotropes in Acute Heart Failure: From Guidelines to Practical Use: Therapeutic Options and Clinical Practice
title_full	Inotropes in Acute Heart Failure: From Guidelines to Practical Use: Therapeutic Options and Clinical Practice
title_fullStr	Inotropes in Acute Heart Failure: From Guidelines to Practical Use: Therapeutic Options and Clinical Practice
title_full_unstemmed	Inotropes in Acute Heart Failure: From Guidelines to Practical Use: Therapeutic Options and Clinical Practice
title_sort	inotropes in acute heart failure: from guidelines to practical use: therapeutic options and clinical practice
publisher	Radcliffe Medical Media
publishDate	2019
url	https://doaj.org/article/0e11d0ccd47948c2b9b2449bc12d3d81
work_keys_str_mv	AT vasilikibistola inotropesinacuteheartfailurefromguidelinestopracticalusetherapeuticoptionsandclinicalpractice AT angelosarfarasmelainis inotropesinacuteheartfailurefromguidelinestopracticalusetherapeuticoptionsandclinicalpractice AT eftihiapolyzogopoulou inotropesinacuteheartfailurefromguidelinestopracticalusetherapeuticoptionsandclinicalpractice AT ignatiosikonomidis inotropesinacuteheartfailurefromguidelinestopracticalusetherapeuticoptionsandclinicalpractice AT johnparissis inotropesinacuteheartfailurefromguidelinestopracticalusetherapeuticoptionsandclinicalpractice
_version_	1718372718162739200

Inotropes in Acute Heart Failure: From Guidelines to Practical Use: Therapeutic Options and Clinical Practice

Ejemplares similares