Design of hidden thermodynamic driving for non-equilibrium systems via mismatch elimination during DNA strand displacement
Synthetic molecular systems require subtle control over their thermodynamics and reaction kinetics to implement features such as catalysis. Here the authors propose using mismatches in a DNA duplex to drive catalytic reactions forward whilst maintaining tight catalytic control.
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Nature Portfolio
2020
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oai:doaj.org-article:0e14c3f417da4a58968040c4405b62d22021-12-02T16:49:45ZDesign of hidden thermodynamic driving for non-equilibrium systems via mismatch elimination during DNA strand displacement10.1038/s41467-020-16353-y2041-1723https://doaj.org/article/0e14c3f417da4a58968040c4405b62d22020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16353-yhttps://doaj.org/toc/2041-1723Synthetic molecular systems require subtle control over their thermodynamics and reaction kinetics to implement features such as catalysis. Here the authors propose using mismatches in a DNA duplex to drive catalytic reactions forward whilst maintaining tight catalytic control.Natalie E. C. HaleyThomas E. OuldridgeIsmael Mullor RuizAlessandro GeraldiniArd A. LouisJonathan BathAndrew J. TurberfieldNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020) |
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Science Q Natalie E. C. Haley Thomas E. Ouldridge Ismael Mullor Ruiz Alessandro Geraldini Ard A. Louis Jonathan Bath Andrew J. Turberfield Design of hidden thermodynamic driving for non-equilibrium systems via mismatch elimination during DNA strand displacement |
description |
Synthetic molecular systems require subtle control over their thermodynamics and reaction kinetics to implement features such as catalysis. Here the authors propose using mismatches in a DNA duplex to drive catalytic reactions forward whilst maintaining tight catalytic control. |
format |
article |
author |
Natalie E. C. Haley Thomas E. Ouldridge Ismael Mullor Ruiz Alessandro Geraldini Ard A. Louis Jonathan Bath Andrew J. Turberfield |
author_facet |
Natalie E. C. Haley Thomas E. Ouldridge Ismael Mullor Ruiz Alessandro Geraldini Ard A. Louis Jonathan Bath Andrew J. Turberfield |
author_sort |
Natalie E. C. Haley |
title |
Design of hidden thermodynamic driving for non-equilibrium systems via mismatch elimination during DNA strand displacement |
title_short |
Design of hidden thermodynamic driving for non-equilibrium systems via mismatch elimination during DNA strand displacement |
title_full |
Design of hidden thermodynamic driving for non-equilibrium systems via mismatch elimination during DNA strand displacement |
title_fullStr |
Design of hidden thermodynamic driving for non-equilibrium systems via mismatch elimination during DNA strand displacement |
title_full_unstemmed |
Design of hidden thermodynamic driving for non-equilibrium systems via mismatch elimination during DNA strand displacement |
title_sort |
design of hidden thermodynamic driving for non-equilibrium systems via mismatch elimination during dna strand displacement |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/0e14c3f417da4a58968040c4405b62d2 |
work_keys_str_mv |
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1718383199242944512 |