Involvement of the Eukaryote-Like Kinase-Phosphatase System and a Protein That Interacts with Penicillin-Binding Protein 5 in Emergence of Cephalosporin Resistance in Cephalosporin-Sensitive Class A Penicillin-Binding Protein Mutants in <named-content content-type="genus-species">Enterococcus faecium</named-content>
ABSTRACT The intrinsic resistance of Enterococcus faecium to ceftriaxone and cefepime (here referred to as “cephalosporins”) is reliant on the presence of class A penicillin-binding proteins (Pbps) PbpF and PonA. Mutants lacking these Pbps exhibit cephalosporin susceptibility that is reversible by e...
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Autores principales: | Charlene Desbonnet, Amelia Tait-Kamradt, Monica Garcia-Solache, Paul Dunman, Jeffrey Coleman, Michel Arthur, Louis B. Rice |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2016
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Materias: | |
Acceso en línea: | https://doaj.org/article/0e21ddea2be3440793cb23110dbae309 |
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