Impairment of the activin A autocrine loop by lopinavir reduces self-renewal of distinct human adipose progenitors

Impairment of the activin A autocrine loop by lopinavir reduces self-renewal of distinct human adipose progenitors

Abstract Maintenance of the adipose tissue requires a proper balance between self-renewal and differentiation of adipose progenitors (AP). Any deregulation leads either to fat overexpansion and obesity or fat loss and consequent lipodystrophies. Depending on the fat pad location, APs and adipocytes...

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Autores principales: Christophe Ravaud, Martin Paré, Stéphane Azoulay, Christian Dani, Annie Ladoux
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/0e2ec10c8aec4b0c99693f6c740bebc0
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