Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice

Adipose tissue expansion occurs via enlargement of adipocytes as well as the generation of new fat cells, the latter being associated with more favorable metabolic outcomes. Here, the authors show that activation of adipocyte Piezo1 results in release of FGF1 and stimulates the differentiation of ad...

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Autores principales:	ShengPeng Wang, Shuang Cao, Malika Arhatte, Dahui Li, Yue Shi, Sabrina Kurz, Jiong Hu, Lei Wang, Jingchen Shao, Ann Atzberger, Zheng Wang, Changhe Wang, Weijin Zang, Ingrid Fleming, Nina Wettschureck, Eric Honoré, Stefan Offermanns
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0e2f059a9f5a4a848971d75c46d12a7f
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spelling	oai:doaj.org-article:0e2f059a9f5a4a848971d75c46d12a7f2021-12-02T14:40:40ZAdipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice10.1038/s41467-020-16026-w2041-1723https://doaj.org/article/0e2f059a9f5a4a848971d75c46d12a7f2020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16026-whttps://doaj.org/toc/2041-1723Adipose tissue expansion occurs via enlargement of adipocytes as well as the generation of new fat cells, the latter being associated with more favorable metabolic outcomes. Here, the authors show that activation of adipocyte Piezo1 results in release of FGF1 and stimulates the differentiation of adipocyte precursor cells.ShengPeng WangShuang CaoMalika ArhatteDahui LiYue ShiSabrina KurzJiong HuLei WangJingchen ShaoAnn AtzbergerZheng WangChanghe WangWeijin ZangIngrid FlemingNina WettschureckEric HonoréStefan OffermannsNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q ShengPeng Wang Shuang Cao Malika Arhatte Dahui Li Yue Shi Sabrina Kurz Jiong Hu Lei Wang Jingchen Shao Ann Atzberger Zheng Wang Changhe Wang Weijin Zang Ingrid Fleming Nina Wettschureck Eric Honoré Stefan Offermanns Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice
description	Adipose tissue expansion occurs via enlargement of adipocytes as well as the generation of new fat cells, the latter being associated with more favorable metabolic outcomes. Here, the authors show that activation of adipocyte Piezo1 results in release of FGF1 and stimulates the differentiation of adipocyte precursor cells.
format	article
author	ShengPeng Wang Shuang Cao Malika Arhatte Dahui Li Yue Shi Sabrina Kurz Jiong Hu Lei Wang Jingchen Shao Ann Atzberger Zheng Wang Changhe Wang Weijin Zang Ingrid Fleming Nina Wettschureck Eric Honoré Stefan Offermanns
author_facet	ShengPeng Wang Shuang Cao Malika Arhatte Dahui Li Yue Shi Sabrina Kurz Jiong Hu Lei Wang Jingchen Shao Ann Atzberger Zheng Wang Changhe Wang Weijin Zang Ingrid Fleming Nina Wettschureck Eric Honoré Stefan Offermanns
author_sort	ShengPeng Wang
title	Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice
title_short	Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice
title_full	Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice
title_fullStr	Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice
title_full_unstemmed	Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice
title_sort	adipocyte piezo1 mediates obesogenic adipogenesis through the fgf1/fgfr1 signaling pathway in mice
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/0e2f059a9f5a4a848971d75c46d12a7f
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Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice

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