A comprehensive characterization of the cell-free transcriptome reveals tissue- and subtype-specific biomarkers for cancer detection

Cell-free RNA (cfRNA) is a promising analyte for cancer diagnosis. Here, the authors determine the baseline cell-free transcriptome in the absence of cancer and identify tissue- and subtype-specific cfRNA biomarkers in breast and lung cancer patients.

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Autores principales:	Matthew H. Larson, Wenying Pan, Hyunsung John Kim, Ruth E. Mauntz, Sarah M. Stuart, Monica Pimentel, Yiqi Zhou, Per Knudsgaard, Vasiliki Demas, Alexander M. Aravanis, Arash Jamshidi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0e37ebdf6f5749248b3b92b0bd2ac004
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:0e37ebdf6f5749248b3b92b0bd2ac0042021-12-02T18:28:38ZA comprehensive characterization of the cell-free transcriptome reveals tissue- and subtype-specific biomarkers for cancer detection10.1038/s41467-021-22444-12041-1723https://doaj.org/article/0e37ebdf6f5749248b3b92b0bd2ac0042021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22444-1https://doaj.org/toc/2041-1723Cell-free RNA (cfRNA) is a promising analyte for cancer diagnosis. Here, the authors determine the baseline cell-free transcriptome in the absence of cancer and identify tissue- and subtype-specific cfRNA biomarkers in breast and lung cancer patients.Matthew H. LarsonWenying PanHyunsung John KimRuth E. MauntzSarah M. StuartMonica PimentelYiqi ZhouPer KnudsgaardVasiliki DemasAlexander M. AravanisArash JamshidiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Matthew H. Larson Wenying Pan Hyunsung John Kim Ruth E. Mauntz Sarah M. Stuart Monica Pimentel Yiqi Zhou Per Knudsgaard Vasiliki Demas Alexander M. Aravanis Arash Jamshidi A comprehensive characterization of the cell-free transcriptome reveals tissue- and subtype-specific biomarkers for cancer detection
description	Cell-free RNA (cfRNA) is a promising analyte for cancer diagnosis. Here, the authors determine the baseline cell-free transcriptome in the absence of cancer and identify tissue- and subtype-specific cfRNA biomarkers in breast and lung cancer patients.
format	article
author	Matthew H. Larson Wenying Pan Hyunsung John Kim Ruth E. Mauntz Sarah M. Stuart Monica Pimentel Yiqi Zhou Per Knudsgaard Vasiliki Demas Alexander M. Aravanis Arash Jamshidi
author_facet	Matthew H. Larson Wenying Pan Hyunsung John Kim Ruth E. Mauntz Sarah M. Stuart Monica Pimentel Yiqi Zhou Per Knudsgaard Vasiliki Demas Alexander M. Aravanis Arash Jamshidi
author_sort	Matthew H. Larson
title	A comprehensive characterization of the cell-free transcriptome reveals tissue- and subtype-specific biomarkers for cancer detection
title_short	A comprehensive characterization of the cell-free transcriptome reveals tissue- and subtype-specific biomarkers for cancer detection
title_full	A comprehensive characterization of the cell-free transcriptome reveals tissue- and subtype-specific biomarkers for cancer detection
title_fullStr	A comprehensive characterization of the cell-free transcriptome reveals tissue- and subtype-specific biomarkers for cancer detection
title_full_unstemmed	A comprehensive characterization of the cell-free transcriptome reveals tissue- and subtype-specific biomarkers for cancer detection
title_sort	comprehensive characterization of the cell-free transcriptome reveals tissue- and subtype-specific biomarkers for cancer detection
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0e37ebdf6f5749248b3b92b0bd2ac004
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A comprehensive characterization of the cell-free transcriptome reveals tissue- and subtype-specific biomarkers for cancer detection

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