Fecal microbiota transplantation in HIV: A pilot placebo-controlled study

It is unknown whether capsulized fecal microbiota transplantation (FMT) can modify the microbiota of people with HIV. Here, the authors report the results of a pilot double-blind study, where 30 HIV-infected subjects on ART were randomized to either weekly oral FMT capsules or placebo for 8 weeks, a...

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Autores principales:	Sergio Serrano-Villar, Alba Talavera-Rodríguez, María José Gosalbes, Nadia Madrid, José A. Pérez-Molina, Ryan J. Elliott, Beatriz Navia, Val F. Lanza, Alejandro Vallejo, Majdi Osman, Fernando Dronda, Shrish Budree, Javier Zamora, Carolina Gutiérrez, Mónica Manzano, María Jesús Vivancos, Raquel Ron, Javier Martínez-Sanz, Sabina Herrera, Uxua Ansa, Andrés Moya, Santiago Moreno
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0e424965dca6462389ec2ceec3d41390
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spelling	oai:doaj.org-article:0e424965dca6462389ec2ceec3d413902021-12-02T14:03:40ZFecal microbiota transplantation in HIV: A pilot placebo-controlled study10.1038/s41467-021-21472-12041-1723https://doaj.org/article/0e424965dca6462389ec2ceec3d413902021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21472-1https://doaj.org/toc/2041-1723It is unknown whether capsulized fecal microbiota transplantation (FMT) can modify the microbiota of people with HIV. Here, the authors report the results of a pilot double-blind study, where 30 HIV-infected subjects on ART were randomized to either weekly oral FMT capsules or placebo for 8 weeks, and show that transplanted microbiota successfully engrafts and is able to attenuate HIV-associated dysbiosis.Sergio Serrano-VillarAlba Talavera-RodríguezMaría José GosalbesNadia MadridJosé A. Pérez-MolinaRyan J. ElliottBeatriz NaviaVal F. LanzaAlejandro VallejoMajdi OsmanFernando DrondaShrish BudreeJavier ZamoraCarolina GutiérrezMónica ManzanoMaría Jesús VivancosRaquel RonJavier Martínez-SanzSabina HerreraUxua AnsaAndrés MoyaSantiago MorenoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sergio Serrano-Villar Alba Talavera-Rodríguez María José Gosalbes Nadia Madrid José A. Pérez-Molina Ryan J. Elliott Beatriz Navia Val F. Lanza Alejandro Vallejo Majdi Osman Fernando Dronda Shrish Budree Javier Zamora Carolina Gutiérrez Mónica Manzano María Jesús Vivancos Raquel Ron Javier Martínez-Sanz Sabina Herrera Uxua Ansa Andrés Moya Santiago Moreno Fecal microbiota transplantation in HIV: A pilot placebo-controlled study
description	It is unknown whether capsulized fecal microbiota transplantation (FMT) can modify the microbiota of people with HIV. Here, the authors report the results of a pilot double-blind study, where 30 HIV-infected subjects on ART were randomized to either weekly oral FMT capsules or placebo for 8 weeks, and show that transplanted microbiota successfully engrafts and is able to attenuate HIV-associated dysbiosis.
format	article
author	Sergio Serrano-Villar Alba Talavera-Rodríguez María José Gosalbes Nadia Madrid José A. Pérez-Molina Ryan J. Elliott Beatriz Navia Val F. Lanza Alejandro Vallejo Majdi Osman Fernando Dronda Shrish Budree Javier Zamora Carolina Gutiérrez Mónica Manzano María Jesús Vivancos Raquel Ron Javier Martínez-Sanz Sabina Herrera Uxua Ansa Andrés Moya Santiago Moreno
author_facet	Sergio Serrano-Villar Alba Talavera-Rodríguez María José Gosalbes Nadia Madrid José A. Pérez-Molina Ryan J. Elliott Beatriz Navia Val F. Lanza Alejandro Vallejo Majdi Osman Fernando Dronda Shrish Budree Javier Zamora Carolina Gutiérrez Mónica Manzano María Jesús Vivancos Raquel Ron Javier Martínez-Sanz Sabina Herrera Uxua Ansa Andrés Moya Santiago Moreno
author_sort	Sergio Serrano-Villar
title	Fecal microbiota transplantation in HIV: A pilot placebo-controlled study
title_short	Fecal microbiota transplantation in HIV: A pilot placebo-controlled study
title_full	Fecal microbiota transplantation in HIV: A pilot placebo-controlled study
title_fullStr	Fecal microbiota transplantation in HIV: A pilot placebo-controlled study
title_full_unstemmed	Fecal microbiota transplantation in HIV: A pilot placebo-controlled study
title_sort	fecal microbiota transplantation in hiv: a pilot placebo-controlled study
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0e424965dca6462389ec2ceec3d41390
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Fecal microbiota transplantation in HIV: A pilot placebo-controlled study

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