Correlation between glycemic variability and gastroesophageal reflux in adolescentswith type 1 diabetes mellitus

Aims. To estimate an impact of glycemic variability on the development of gastroesophageal reflux disease (GERD) in adolescents with type 1 diabetes mellitus (T1DM). Materials and methods. We enrolled 33 patients with T1DM aged from 12 to 17 years. 24-h pH-monitoring was performed with ?Gas- trosk...

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Autores principales: I L Alimova, S E Kostyakov
Formato: article
Lenguaje:EN
RU
Publicado: Endocrinology Research Centre 2013
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Acceso en línea:https://doaj.org/article/0e46542e09d947a7a200d775e819a809
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Sumario:Aims. To estimate an impact of glycemic variability on the development of gastroesophageal reflux disease (GERD) in adolescents with type 1 diabetes mellitus (T1DM). Materials and methods. We enrolled 33 patients with T1DM aged from 12 to 17 years. 24-h pH-monitoring was performed with ?Gas- troskan 24? system (Istok-Sistema, Fryazino); 24-h continuous glucose monitoring utilized CGMS MMT-7310 (Medtronic Minimed, USA) with subsequent night-time analysis. Results. As compared to stable night-time glycemia controls (SD 2.0 mmol/L) showed longer period of esophageal acidification (17% [2?58]; p